Results 271 to 280 of about 9,170,751 (397)

Systematic analysis of the target recognition and repression by the Pumilio proteins. [PDF]

Nucleic Acids Res
Farberov S, Ulitsky I.
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

TDP-SAR: Task-Driven Pruning Method for Synthetic Aperture Radar Target Recognition Convolutional Neural Network Model. [PDF]

Sensors (Basel)
Zheng T, Wu Q, Yu C.
europepmc   +1 more source

Morphological Image Pyramids for Automatic Target Recognition

, 1997
Wei Chen
openalex   +1 more source

Author response: Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition

, 2015
Zhu Liu, Zhou Gong, Wenxue Jiang, Ju Hwan Yang, Wenkai Zhu, Da‐Chuan Guo, Wei‐Ping Zhang, Maili Liu, Chun Tang   +8 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Excessive Existence of Positively Charged Amino Acids Caused Off-Target Recognition in the Seed Region of <i>Clostridium butyricum</i> Argonaute. [PDF]

Int J Mol Sci
Ma W, Lyu W, Zhu L.
europepmc   +1 more source

Target Achievement Control Test: Evaluating real-time myoelectric pattern-recognition control of multifunctional upper-limb prostheses

, 2011
Ann M. Simon, Levi J. Hargrove, Blair A. Lock, Todd Kuiken   +3 more
openalex   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Research progress and prospect of key technologies of fruit target recognition for robotic fruit picking. [PDF]

Front Plant Sci
Liu S, Xue J, Zhang T, Lv P, Qin H, Zhao T.   +5 more
europepmc   +1 more source