Results 51 to 60 of about 461,783 (265)

Target Window Reliability

open access: yes, 2016
The target window design implemented and tested in experiments at ANL have performed without failure for the available beam of 6 mm FWHM on a 12 mm diameter target. However, scaling that design to a 25 mm diameter target size for a 12 mm FWHM beam has proven problematic.
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A methodology to determine the target reliability of natural gas pipeline systems based on risk acceptance criteria of pipelines

open access: yesJournal of Pipeline Science and Engineering
The reliable operation of the natural gas pipeline system is directly related to natural gas supply security, and it is vital to determine the target reliability of the natural gas pipeline system when assessing whether the system is reliable.
Xiangying Shan   +9 more
doaj   +1 more source

Shear Strength Reduction Factor of Prestressed Hollow-Core Slab Units Based on the Reliability Approach

open access: yesAdvances in Materials Science and Engineering, 2017
This study investigated the shear design equations for prestressed hollow-core (PHC) slabs and examined the suitability of strength reduction factors based on the structural reliability theory.
Hae-Chang Cho   +5 more
doaj   +1 more source

Effects of attention and reliability on the performance of online medical crowdfunding projects: The moderating role of target amount

open access: yesJournal of Management Science and Engineering, 2020
Medical crowdfunding platform helps numerous patients access enthusiastic donors and address financial difficulties, but many crowdfunding projects fail to reach their target amount.
Shan Liu, Tingwei Cheng, Hao Wang
doaj   +1 more source

System Reliability Growth Analysis during Warranty [PDF]

open access: yesInternational Journal of Mathematical, Engineering and Management Sciences, 2019
This paper presents system reliability growth analysis using actual field failure data. The primary objective of the system reliability growth is to improve the achievement of system reliability performance during system reliability demonstration, in ...
James Li   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Feasibility, reliability and validity of a modified approach to goal attainment scaling to measure goal outcomes following cognitive remediation in a residential substance use disorder rehabilitation setting

open access: yesAustralian Journal of Psychology, 2023
Objective Although person-centred outcome measures have been recommended to evaluate cognitive rehabilitation interventions, few validated measures have been developed for this purpose.
Jamie Berry, Ely M. Marceau, Jo Lunn
doaj   +1 more source

How reliable are ligand-centric methods for Target Fishing? [PDF]

open access: yesFrontiers in Chemistry, 2015
Computational methods for Target Fishing (TF), also known as Target Prediction or Polypharmacology Prediction, can be used to discover new targets in small-molecule drugs. This may result in repositioning the drug in a new indication or improving our current understanding of its efficacy and side effects.
Peón, Antonio   +2 more
openaire   +4 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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