Results 131 to 140 of about 8,510,768 (280)

Impact of a Novel W2027L Mutation and Non-Target Site Resistance on Acetyl-CoA Carboxylase-Inhibiting Herbicides in a French Lolium multiflorum Population. [PDF]

Genes (Basel), 2021
Kaundun SS, Downes J, Jackson LV, Hutchings SJ, Mcindoe E.   +4 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Target‐site mutations Ile1781Leu and Ile2041Asn in the ACCase2 gene confer resistance to fluazifop‐p‐butyl and pinoxaden herbicides in a johnsongrass accession from Arkansas, USA

Plant Direct
Johnsongrass [Sorghum halepense (L.) Pers.] is a troublesome weed species in different agricultural and non‐agricultural areas. Because of its biology, reproductive system, and seed production, effective management is challenging.
Fidel González‐Torralva, Jason K. Norsworthy   +1 more
doaj   +1 more source

The intensity of non-target site mechanisms influences the level of resistance of sourgrass to glyphosate [PDF]

Communications in Plant Sciences, 2014
Non-target site mechanisms are involved in the resistance of sourgrass (Digitaria insularis) to glyphosate. Studies on the 14C-glyphosate absorption and translocation as well as the detection of glyphosate and its metabolites in sourgrass plants were ...
Flávia Regina da Costa, Leonardo Bianco de Carvalho, Pedro Luis da Costa Aguiar Alves, Rafael De Prado   +3 more
doaj  

Detection of target site resistance to pyrethroids and organophosphates in the horn fly using multiplex polymerase chain reaction

, 2010
The horn fly, Haematobia irritans L., is an obligate blood-feeding fly and the primary insect pest parasitizing cattle in the United States. Pesticide resistance has become a substantial problem for cattle producers, and although several mechanisms of ...
Bendele, K. G., Foil, L. D., Guerrero, F. D.   +2 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

The genetic architecture of target-site resistance to pyrethroid insecticides in the African malaria vectors Anopheles gambiae and Anopheles coluzzii. [PDF]

Mol Ecol, 2021
Clarkson CS, Miles A, Harding NJ, O'Reilly AO, Weetman D, Kwiatkowski D, Donnelly MJ, Anopheles gambiae 1000 Genomes Consortium.   +7 more
europepmc   +1 more source

Detection of target-site mutations linked to pyrethroid resistance in Musca domestica L. (Diptera: Muscidae) in Northern Italy

, 2015
Pyrethroid insecticides have been widely used to control housefly infestations and they still remain an important tool above all in urban and household environments. However their efficacy is affected by insecticide resistance mechanisms.
Puggioni, Vincenzo, Anaclerio, Matteo, Mazzoni, Emanuele, Chiesa, Olga, Panini, Michela   +4 more
core  

Target and Non–target site Mechanisms Confer Resistance to Glyphosate in Canadian Accessions ofConyza canadensis

, 2017
Glyphosate-resistant populations ofConyza canadensishave been spreading at a rapid rate in Ontario, Canada, since first being documented in 2010. Determining the genetic relationship among existing Ontario populations is necessary to understand the ...
Jichul Bae, Eric R. Page, François J. Tardif, Martin Laforest, Robert E. Nurse, Istvan Rajcan, Christopher M. Grainger   +6 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source