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Target-site and non-target site resistance mechanisms are associated with iodosulfuron resistance in Lolium perenne L.

2023
Resistance to iodosulfuron, a herbicide targeting acetolactate synthase (ALS), was identified and characterised in a population of Lolium perenne L. from Canterbury, New Zealand. The resistant population was 264 times more resistant to iodosulfuron than a susceptible population, based on a ratio of the rate corresponding to a 50% reduction in resistant
Ghanizadeh, Hossein   +4 more
openaire   +1 more source

Cross-resistance to photosystem II inhibitors observed in target site–resistant but not in non–target site resistant common ragweed (Ambrosia artemisiifolia)

Weed Science, 2022
AbstractThe full spectrum of herbicide resistance in a weed can vary according to the mechanistic basis and cannot be implied from the selective pressure. Common ragweed (Ambrosia artemisiifolia L.) is an important weed species of horticultural crops that has developed resistance to linuron based on either target site– or non–target site resistance ...
Martin Laforest   +5 more
openaire   +1 more source

Target and non‐target site mechanisms of fungicide resistance and their implications for the management of crop pathogens

Pest Management Science, 2023
Abstract Fungicides are indispensable for high‐quality crops, but the rapid emergence and evolution of fungicide resistance have become the most important issues in modern agriculture. Hence, the sustainability and profitability of agricultural production have been challenged due to the limited number of fungicide chemical classes ...
Adriano Francis Dorigan   +4 more
openaire   +2 more sources

Bacterial resistance to antibiotics: Modified target sites

Advanced Drug Delivery Reviews, 2005
Alteration in the target sites of antibiotics is a common mechanism of resistance. Examples of clinical strains showing resistance can be found for every class of antibiotic, regardless of the mechanism of action. Target site changes often result from spontaneous mutation of a bacterial gene on the chromosome and selection in the presence of the ...
openaire   +2 more sources

Altered target sites as a mechanism of herbicide resistance

Crop Protection, 2000
Abstract Over 200 distinct herbicide resistant weed biotypes have evolved worldwide. In most of these, resistance is conferred by an altered target site, i.e. a modified target protein with reduced affinity for the herbicide(s) in question. This has been documented for herbicides that target most major known sites of action, including those that ...
Malcolm D. Devine, Amit Shukla
openaire   +1 more source

Non-target Site Mechanisms of Resistance to Herbicides

Critical Reviews in Plant Sciences, 2017
ABSTRACTEvolution of resistance in weeds to herbicides is threatening world agricultural production. Weed management has become more complicated with the development of non-target site resistance (NTSR) to herbicides in weeds. The NTSR mechanisms can be caused by herbicide metabolism, altered patterns of translocation, and herbicide absorption ...
Hossein Ghanizadeh, Kerry C. Harrington
openaire   +1 more source

R-factor trimethoprim resistance mechanism: An insusceptible target site

Biochemical and Biophysical Research Communications, 1974
Abstract R-factor R388 increases the resistance of Escherichia coli to trimethoprim by 10,000 fold, and mediates the synthesis of an addional dihydrofolate reductase that is less susceptible to trimethoprim by a similar order of magnitude. The dihydrofolate reductase conferred by the R-factor was of a larger molecular weight than the wild-type ...
S G, Amyes, J T, Smith
openaire   +2 more sources

Overcoming drug resistance: targeting more than one site

Leukemia Research, 2002
Activation of the molecular machinery of programmed cell death (apoptosis) is a convergence point for many cytotoxic agents, irrespective of the primary mechanism of action. Indeed, apoptosis is induced in response to DNA strand breaks caused by such mechanistically diverse anti-leukemic drugs as the nucleoside cytosine arabinoside (ara-C ...
Judith E, Karp, Bijoyesh P, Mookerjee
openaire   +2 more sources

Conyza bonariensis resistance to glyphosate and ALS inhibitors involves target and non-target site resistance

Pesticide Biochemistry and Physiology
Herbicide resistance in Conyza bonariensis (hairy fleabane) poses a significant challenge to agricultural systems worldwide. The genetic variability and prolific seed production of this species contribute significantly to its adaptative potential and fast spread in the agricultural fields.
Tiago Edu, Kaspary   +5 more
openaire   +2 more sources

Both target-site and non-target-site resistance mechanisms confer mesosulfuron-methyl resistance in Silene conoidea L.

Pesticide Biochemistry and Physiology
Silene conoidea L., a common weed in wheat fields, is mainly controlled by acetolactate synthase (ALS)-inhibiting herbicides such as mesosulfuron-methyl. In this study, we investigated a mesosulfuron-methyl resistant population to elucidate the resistance mechanisms.
Xinhui, Xue   +7 more
openaire   +2 more sources

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