Results 131 to 140 of about 630,172 (289)

Additional file 6: Figure S6. of ALOMYbase, a resource to investigate non-target-site-based resistance to herbicides inhibiting acetolactate-synthase (ALS) in the major grass weed Alopecurus myosuroides (black-grass)

, 2016
Jeanne Gardin, Jérôme Gouzy, Sébastien Carrère, Christophe Délye   +3 more
openalex   +1 more source

Multiple insecticide resistance target sites in adult field strains of An. gambiae (s.l.) from southeastern Senegal [PDF]

, 2020
El Hadji Diouf, El Hadji Amadou Niang, Badara Samb, Cheikh Tidiane Diagne, Mbaye Diouf, Abdoulaye Konaté, Ibrahima Dia, Ousmane Faye, Lassana Konaté   +8 more
openalex   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Target Site–Based and Non–Target Site Based Resistance to ALS Inhibitors in Palmer Amaranth (Amaranthus palmeri) [PDF]

, 2017
Sridevi Nakka, Curtis R. Thompson, Dallas E. Peterson, Mithila Jugulam   +3 more
openalex   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Determination of the Mechanisms of MCPA Resistance in Amaranthus powellii

Plant Direct
Resistance to 2‐methyl‐4‐chloro‐phenoxyacetic acid (MCPA) was recently confirmed in a population of green pigweed (Amaranthus powellii) from Dresden, Ontario, Canada, with a resistance factor of 4.4. Resistance to synthetic auxin herbicides in Amaranthus
Isabelle Aicklen, Mithila Jugulam, Todd Gaines, William Kramer, Martin Laforest, Darren Robinson, Peter Sikkema, François Tardif   +7 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Investigation of the target-site resistance of EPSP synthase mutants P106T and T102I/P106S against glyphosate. [PDF]

RSC Adv, 2020
Fonseca ECM, da Costa KS, Lameira J, Alves CN, Lima AH.   +4 more
europepmc   +1 more source

Additional file 4: Figure S2. of Site-specific His/Asp phosphoproteomic analysis of prokaryotes reveals putative targets for drug resistance

, 2017
Shu-Jung Lai, I-Fan Tu, Wan‐Ling Wu, Jhih-Tian Yang, Louis Y. P. Luk, Mei‐Chin Lai, Yu-Hsuan Tsai, Shih-Hsiung Wu   +7 more
openalex   +1 more source