Results 211 to 220 of about 630,172 (289)
Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan +7 more
wiley +1 more source
Symbiont-mediated mechanisms of insecticide resistance in insects. [PDF]
Lv C, Xia Q, Yan S.
europepmc +1 more source
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah +13 more
wiley +1 more source
Redefining Antimicrobial Resistance in <i>Acinetobacter baumannii</i>: A Mechanistic Framework Linking Intracellular Antibiotic Activity to Treatment Failure. [PDF]
Elbehiry A +3 more
europepmc +1 more source
Target-site and metabolic resistance against λ-cyhalothrin in cabbage stem flea beetles in Denmark. [PDF]
Dorte Heidi Højland, Michael Kristensen
openalex
Genetic studies on the target-site resistance to sulfonylurea herbicides in Schoenoplectus juncoides
Yoshinao Sada
openalex +2 more sources
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan +10 more
wiley +1 more source
Research progress on HIV-1 structural proteins and antiviral therapies. [PDF]
Wang H, Yuan J, Wang H.
europepmc +1 more source
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin +14 more
wiley +1 more source

