Results 41 to 50 of about 7,696,254 (202)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Differences in Germination of ACCase-Resistant Biotypes Containing Isoleucine-1781-Leucine Mutation and Susceptible Biotypes of Wild Oat (Avena sterilis ssp. ludoviciana)

Plants, 2021
Herbicide resistance can affect seed germination and the optimal conditions required for seed germination, which in turn may impose a fitness cost in resistant populations. Winter wild oat [Avena sterilis L. ssp. ludoviciana (Durieu) Gillet and Magne] is
Fatemeh Benakashani, Jose L. Gonzalez-Andujar, Elias Soltani   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Characterization of Sodium Channel Mutations in the Dengue Vector Mosquitoes Aedes aegypti and Aedes albopictus within the Context of Ongoing Wolbachia Releases in Kuala Lumpur, Malaysia

Insects, 2020
Specific sodium channel gene mutations confer target site resistance to pyrethroid insecticides in mosquitoes and other insects. In Aedes mosquito species, multiple mutations that contribute to resistance vary in their importance around the world.
Noor Afizah Ahmad, Nancy M. Endersby-Harshman, Nur Ruqqayah Mohd Mazni, Nur Zatil Aqmar Mohd Zabari, Siti Nor Syazwani Amran, Muhammad Kamarul Ridhuan Ghazali, Mohd Arif Abdul Karim, Yoon Ling Cheong, Steven P. Sinkins, Nazni Wasi Ahmad, Ary A. Hoffmann   +10 more
doaj   +1 more source

Non-Target Site Resistance in Summer-Emerging Lolium rigidum and the Effect of Alternative Herbicides

Agronomy, 2023
Herbicide resistance is an important weed management issue. Glyphosate is the most dominant herbicide, which controls a broad spectrum of weeds, including grasses such as Lolium rigidum. Lolium rigidum is a major weed of winter crops in Australia that is
Michael Thompson, Bhagirath S. Chauhan
doaj   +1 more source

Characterisation of target-site resistance to ACCase-inhibiting herbicides in the weed Alopecurus myosuroides (black-grass)

, 2003
Resistance to aryloxyphenoxypropionate (AOPP), cyclohexanedione (CHD) and phenylurea herbicides was determined in UK populations of Alopecurus myosuroides Huds. Two populations (Oxford AA1, Notts.
Moss, S. R., Field, L. M., Linda Hall, Stephen R Moss, Cocker, K. M., Brown, A. C., Linda M Field, Kay M Cocker, Amanda C Brown, Hall, L., Moss, Stephen, Field, Lin   +11 more
core   +1 more source

Non‐target site SDHI resistance is present as standing genetic variation in field populations of Zymoseptoria tritici [PDF]

, 2017
BACKGROUND A new generation of more active succinate dehydrogenase (Sdh) inhibitors (SDHIs) is currently widely used to control Septoria leaf blotch in northwest Europe.
Fraaije, B. A., Masao Yamashita, Bart Fraaije, Yamashita, M., Fraaije, Bart   +4 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Status and development of ACCase and ALS inhibitor resistant black-grass (Alopecurus myosuroides Huds.) in neighboring fields in Germany

Julius-Kühn-Archiv, 2012
Neighboring fields in three local areas of southern Germany have been investigated for the infestation level and herbicide resistance structure of black-grass (Alopecurus myosuroides Huds.).
Hess, Martin, Beffa, Roland, Kaiser, Joachim, Laber, Bernd, Menne, Hubert, Strek, Harry   +5 more
doaj   +1 more source

Comparability between insecticide resistance bioassays for mosquito vectors : time to review current methodology? [PDF]

, 2015
Insecticides play an integral role in the control of mosquito-borne diseases. With resistance to insecticides on the rise, surveillance of the target population for optimal choice of insecticides is a necessity.
Müller, Pie, Malone, David, David Malone, Owusu, Henry F, Jančáryová, Danica, Henry F Owusu, Pie Müller, Owusu, Henry F., Danica Jančáryová, Malone D, Müller P, Jančáryová D, Owusu HF   +12 more
core   +1 more source