Results 301 to 310 of about 10,512,166 (412)

Research hotspots and emerging trends in targeted therapy for colorectal cancer: a bibliometric analysis (2000-2023). [PDF]

Discov Oncol
Meng X, Lu Z, Mi F, Sha S, Li T.
europepmc   +1 more source

EFFICIENT GENE DELIVERY TO VASCULAR SMOOTH MUSCLE CELLS USING A NONTOXIC, SYNTHETIC PEPTIDE VECTOR SYSTEM TARGETED TO MEMBRANE INTEGRINS: A FIRST STEP TOWARD THE GENE THERAPY OF CHRONIC REJECTION1

, 2000
Jian‐Mei Li, Louise Collins, Xiaohong Zhang, Kenth Gustafsson, John W. Fabre   +4 more
openalex   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

The multifaceted functions of SPC25 in cancer: from molecular pathways to targeted therapy. [PDF]

Front Med (Lausanne)
Jin Y, Chen M, Chen F, Gao Z, Li X, Hu L, Cai D, Zhao S, Song Z.   +8 more
europepmc   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Molecular mechanisms and targeted therapy of progranulin in metabolic diseases. [PDF]

Front Endocrinol (Lausanne)
Wang X, Liang Y, Yang F, Shi Y, Shao R, Jing R, Yang T, Chu Q, An D, Zhou Q, Song J, Chen H, Liu C.   +12 more
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Precision Microbiome: A New Era of Targeted Therapy with Core Probiotics. [PDF]

Research (Wash D C)
Fang X, Wang Y, Wei H, Huang Y.
europepmc   +1 more source

Targeted photodynamic therapy of breast cancer cells using antibody–phthalocyanine–gold nanoparticle conjugates [PDF]

, 2011
Cook, MJ, Edwards, DR, Moreno, M, Russell, DA, Stuchinskaya, T   +4 more
core   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source