Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi +5 more
wiley +1 more source
Integrated phenotypic analysis, predictive modeling, and identification of novel trait-associated loci in a diverse Theobroma cacao collection. [PDF]
Baek I +10 more
europepmc +1 more source
Effectiveness Assessment of Underwater Area Cruise Based on the ADC Method
ABSTRACT Underwater area surveillance plays a crucial role in upholding national security, safeguarding strategic interests, and mitigating potential threats. Despite its significance, a notable gap persists in the availability of comprehensive models for assessing its effectiveness.
Qingwei Liang +3 more
wiley +1 more source
Mechanistic studies on the effect of berberine on methicillin-resistant Staphylococcus aureus drug resistance through modulation of wall teichoteic acid. [PDF]
Zhou F +8 more
europepmc +1 more source
ABSTRACT The presumptive standards approach to environmental flows offers a method to develop interim guidelines for ecological and social‐cultural flow needs. The approach is based on deriving acceptable percent‐of‐flow limits based on naturalised flows (the absence of depletion or alteration of flow), and it can be an effective precursor to a full ...
Jennifer Lento +6 more
wiley +1 more source
Adoption of Personal Health Records in Dutch Hospitals and Private Medical Clinics: Longitudinal Study. [PDF]
van der Smissen D +5 more
europepmc +1 more source
Abstract Research Summary Access to markets is critical for entrepreneurial success, yet many face significant barriers. This study argues that digital platforms functioning as peer‐to‐peer marketplaces can facilitate entrepreneurial activity by improving market access for new ventures.
Daehyun Kim, Yongwook Paik, Namil Kim
wiley +1 more source
Cefdinir reprograms Gram-positive bacteria to synergize with lysozyme against superbugs. [PDF]
Zhang Q +6 more
europepmc +1 more source
Artificial intelligence adoption and the demand for managerial expertise
Abstract Research Summary This paper examines how firms' adoption of artificial intelligence (AI) relates to the demand for managers and managerial skills. Using a skills‐based measure of AI adoption derived from Lightcast job postings, we show that firms with greater AI adoption post more managerial vacancies and a higher share of such vacancies than ...
Liudmila Alekseeva +3 more
wiley +1 more source
Tunneling Andreev reflection spectroscopy leverages the exponential sensitivity of tunneling current to distinguish between a variety of superconducitng order parameters. Here it is shown that the additivity of excess decay rate enables clear separation of Andreev and quasiparticle currents, fingerprinting the existence of sign changing superconducting
Petro Maksymovych +4 more
wiley +1 more source

