Results 41 to 50 of about 6,710 (210)

Treatment of a young child with multicentric carpotarsal osteolysis exhibiting joint inflammation and dysfunctional bone formation

Bone Reports, 2023
Multicentric carpotarsal osteolysis (MCTO) is a rare skeletal dysplasia characterized by osteolysis of the carpal and tarsal bones. Antiresorptive agents have proven ineffective and the pathogenesis of MCTO remains poorly understood.
Bailey Trinkino, Nina S. Ma
doaj   +1 more source

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

Developmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu, Katja R. MacCharles, Kenneth Kin Lam Wong, Joy M. Richman, Esther M. Verheyen   +4 more
wiley   +1 more source

Three cases of multicentric carpotarsal osteolysis syndrome: a case series

BMC Medical Genetics, 2018
Background Multicentric carpotarsal osteolysis syndrome (MCTO) is characterized by progressive destruction and disappearance of the carpal and tarsal bones associated with nephropathy.
Peong Gang Park, Kee Hyuck Kim, Hye Sun Hyun, Chan Hee Lee, Jin-Su Park, Jeong Hae Kie, Young Hun Choi, Kyung Chul Moon, Hae Il Cheong   +8 more
doaj   +1 more source

A clinical trial of a unidirectional porous tricalcium phosphate filling for defects after resection of benign bone lesions: a prospective multicenter study

Scientific Reports, 2022
Affinos (Kuraray, Japan) is a β-tricalcium phosphate bone substitute with a unidirectional porous structure. This study aimed to investigate its efficacy on the healing process after filling for bone defects.
Kunihiro Ikuta, Yoshihiro Nishida, Takehiro Ota, Satoshi Tsukushi, Eiji Kozawa, Hiroatsu Nakashima, Kenji Yamada, Satoshi Yamashita, Shiro Imagama   +8 more
doaj   +1 more source

Surgical management of dysplasia epiphysealis hemimelica of the posterior medial ankle using a medial malleolar osteotomy: A case report

Foot & Ankle Surgery: Techniques, Reports & Cases, 2021
Dysplasia Epiphysealis Hemimelica (DEH) or Trevor's disease is a rare skeletal condition that forms osteochondroma like lesions in the epiphysis of long bones. This occurs mainly in pediatric patients with a predilection for the lower extremities.
John P. Bonvillian, DPM, Hayden L. Hoffler, DPM, Rebecca M. Steele, MD, Matthew E. Ravish, DO, Bettina M. Gyr, MD   +4 more
doaj   +1 more source

Risk assessment for condylar stress fracture in elite racing Thoroughbreds using standing computed tomography‐based virtual mechanical testing

Equine Veterinary Journal, EarlyView.
Abstract Background Condylar stress fracture of the third metacarpal bone (MC3) is a common catastrophic injury in Thoroughbred racehorses and is associated with parasagittal groove (PSG) subchondral osteolysis. Standing computed tomography (sCT) imaging enables sensitive identification of this fatigue‐induced early subchondral bone injury (SBI), but ...
Nicola L. Brown, Soroush Irandoust, Elleana J. Thom, R. Christopher Whitton, Corinne R. Henak, Peter Muir   +5 more
wiley   +1 more source

Clinical and research applications of synthetic bone substitutes in equine veterinary medicine: A systematic review

Equine Veterinary Journal, EarlyView.
Abstract Background Bone grafting in equine medicine offers a promising contribution to treating orthopaedic developmental diseases and chondral, osteochondral and segmental bone defects. Among grafts, synthetic bone substitutes—alloplastics—show favourable biological properties addressing numerous limitations presented by autografts, xenografts and ...
Katarzyna Skierbiszewska, Bernard Turek, Tomasz Jasiński, Michał Kaczorowski, Natalia Kozłowska, Julia Higuchi, Małgorzata Domino   +6 more
wiley   +1 more source

Neo‐Taphonomic Analysis of Prey Bone Remains Accumulated by Golden Eagle (Aquila chrysaetos): A Case of Nests in Southern France

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT The golden eagle (Aquila chrysaetos) nests in rock cavities where it accumulates prey bone remains during the breeding season. Because nests can be reoccupied from year to year, these faunal elements can form remarkable bone accumulations and, in the sub‐fossil record, be mixed with assemblages derived from human or other predator activities ...
Juliette Ripond, Véronique Laroulandie, Jean‐Baptiste Mallye, Renaud Nadal, Patrick Bayle, Christian Itty   +5 more
wiley   +1 more source

A Quantitative Approach to Record Skeletal Manifestations of Leprosy and Its Application to St Mary Magdalen Leprosarium, Winchester

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT This paper presents and tests a new method for publishing and diagnosing leprosy‐related skeletal lesions while making available the leprosy‐related demographic data and pathology for St Mary Magdalen, Winchester (MMW). This method can facilitate interstudy comparisons of leprosy prevalence and severity by improving data comparability.
A. A. Blom, H. Dawson‐Hobbis, S. Gross, K. White‐Iribhogbe, V. J. Schuenemann, S. A. Inskip   +5 more
wiley   +1 more source

Comparing leukocyte‐ and thrombocyte‐rich fibrin and autologous grafts for the treatment of experimentally induced wounds in the tarsometatarsus of chickens

Veterinary Record, EarlyView.
Abstract Background Managing open wounds in birds is challenging. This study compared leukocyte‐ and thrombocyte‐rich fibrin (L‐TRF) and autologous grafts for treating wounds in the tarsometatarsus of chickens. Methods Full‐thickness wounds were experimentally induced in the tarsometatarsus of 23 healthy adult chickens.
Vivian Ferreira Rech, Sheila Canevese Rahal, Renata Dalcol Mazaro, Luna Scarpari Rolim, Guilherme Rech Cassanego, Matheus Yuri Dos Santos, Rafael Almeida Fighera   +6 more
wiley   +1 more source