Results 131 to 140 of about 24,679,585 (287)

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

BrainEffeX: A web app for exploring fMRI effect sizes

Aperture Neuro
Effect size estimation is crucial for power analyses and experimental design, but poses unique challenges in fMRI research due to the complexity of the data and analysis techniques.
Hallee Shearer, Matt Rosenblatt, Jean Ye, Rongtao Jiang, Link Tejavibulya, Maya L. Foster, Qinghao Liang, Javid Dadashkarimi, Margaret L. Westwater, Catherine Cahill, Iris Cheng, Alexandra Fischbach, Ashley Humphries, Max J. Rolison, Hannah Peterson, Brendan D. Adkinson, Saloni Mehta, Chris Camp, Thomas E. Nichols, Joshua Curtiss, Dustin Scheinost, Stephanie Noble   +21 more
doaj   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Multimodal imaging-based targeting approach for network-level brain stimulation

Frontiers in Neuroscience
IntroductionNeural network effects of transcranial direct current stimulation (tDCS) are poorly understood. Here, we introduce a prospective, empirically informed, multimodal functional magnetic resonance imaging (fMRI) framework for guiding target ...
Alireza Shahbabaie, Mohamed Abdelmotaleb, Harun Kocataş, Filip Niemann, Daria Antonenko, Agnes Flöel, Agnes Flöel, Marcus Meinzer   +7 more
doaj   +1 more source

Novel planning pipeline utilizing the Surgical Theater system for pediatric epilepsy surgery

Epilepsia Open, EarlyView.
Abstract Objective Advances in the analysis and collation of radiographic datasets have enhanced presurgical planning for various neurosurgical procedures, including clipping of cerebral aneurysms, surgical resection of tumors, and arteriovenous malformation management.
Lisa B. E. Shields, Hunain Abri, Cemal Karakas, Shannon D. Davis, Ian S. Mutchnick   +4 more
wiley   +1 more source

Generating synthetic task-based brain fingerprints for population neuroscience using deep learning

Communications Biology
Task-based functional magnetic resonance imaging (fMRI) reveals individual differences in neural correlates of cognition but faces scalability challenges due to cognitive demands, protocol variability, and limited task coverage in large datasets.
Emin Serin, Kerstin Ritter, Gunter Schumann, Tobias Banaschewski, Andre Marquand, Henrik Walter, On behalf of the environMENTAL consortium   +6 more
doaj   +1 more source

Functional alteration of divided attention in people living with HIV based on a task-fMRI study

Frontiers in Neuroscience
BackgroundImpaired attention is a key feature of HIV-associated brain damage, and people living with HIV (PLWH) often have potential visual–auditory perceptual deficits.
Junzhuo Chen, Zhongtian Guan, Chuanke Hou, Xingyuan Jiang, Haixia Luo, Fan Xu, Aixin Li, Xi Wang, Wei Wang, Chunlin Li, Hongjun Li   +10 more
doaj   +1 more source

Imaging haemodynamic changes related to seizures: comparison of EEG-based general linear model, independent component analysis of fMRI and intracranial EEG [PDF]

, 2010
Background: Simultaneous EEG-fMRI can reveal haemodynamic changes associated with epileptic activity which may contribute to understanding seizure onset and propagation. Methods: Nine of 83 patients with focal epilepsy undergoing pre-surgical evaluation
Laufs, H., Lhatoo, S., Guye, M., Rodionov, R., McEvoy, A., Carmichael, D., Thornton, R.C., Vulliemoz, S., Cannadathu, S., Vaudano, A.   +9 more
core  

Abnormal functional connectivity patterns in temporal lobe epilepsy—An international ENIGMA‐epilepsy study

Epilepsia Open, EarlyView.
Abstract Objectives Temporal lobe epilepsy (TLE) impacts multiple brain networks. Aberrant functional connectivity has been demonstrated in resting‐state networks (RSNs) that mediate higher brain functions in TLE. This study aimed to identify the reproducible patterns of altered functional connectivity in TLE in a large, international cohort through ...
Victoria Ives‐Deliperi, Jonathan Ipser, James T. Butler, Heath Pardoe, Hamid Soltanian‐Zadeh, Christian Rummel, Roland Wiest, Simon S. Keller, Barbara A. K. Kreilkamp, Anna Elisabetta Vaudano, Alice Ballerini, Stefano Meletti, Gerard Hall, Peter Taylor, Luis Concha, Alfonso Fajardo‐Valdez, Raphael Fernandes Casseb, Fernando Cendes, Clarissa L. Yasuda, Louis Lemieux, John S. Duncan, Esmaeil Davoodi‐Bodj, Orrin Devinsky, Sophia I. Thomopoulos, Dan J. Stein, Paul M. Thompson, Sanjay M. Sisodiya, Taha Gholipour, Carrie R. McDonald   +28 more
wiley   +1 more source

The role of the left head of caudate in suppressing irrelevant words [PDF]

, 2010
Suppressing irrelevant words is essential to successful speech production and is expected to involve general control mechanisms that reduce interference from task-unrelated processing.
Joseph T. Devlin, Price, C.J., Nilufa Ali, Green, D.W., Devlin, J.T., Ferath Kherif, David W. Green, Cathy J. Price, Ali, N., Kherif, F.   +9 more
core