Results 251 to 260 of about 2,620,157 (317)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Frailty dimensions and cognitive function in relation to dual-task cost: A multidomain analysis in community-dwelling older adults. [PDF]

J Frailty Aging
Heyzer L, Low K, Tan CN, Yeo A, Chia JQ, Chew J, Kua J, Lim WS.   +7 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Navigating Knowledge: Effects of State Curiosity on Children's Word Learning and Information Seeking. [PDF]

Dev Sci
Caunt A, Dordoy S, Abu-Zhaya R, Smith AD.   +3 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Employee political skill, leader-member exchange, and promotability: the moderating role of task performance. [PDF]

Front Psychol
Shang C, Chen S, Li Z.
europepmc   +1 more source

Developing Context-Appropriate Emotions: Longitudinal Changes in Emotion Reactivity and Emotion Regulation From 6 to 12 Months. [PDF]

Dev Sci
Suata ZM, Daubney K, Kostyrka-Allchorne K, Wass SV, Sonuga-Barke E.   +4 more
europepmc   +1 more source

The Effects of Different Attentional Focus During Walking on Prefrontal Cortical Activation in Young Healthy Adults. [PDF]

Eur J Neurosci
Grain T, Ozsancak C, Bonnal J, Auzou P, Prieur F.   +4 more
europepmc   +1 more source

Memory Performance in Adolescents Living With Obesity: Brain Activation During Encoding and Retrieval in a Case-Control Study. [PDF]

Obes Sci Pract
Emmie Bouvier A, Dilharreguy B, Sanz-Arigita E, Barat P, Berthoz S, Barse E, Marighetto A, Ferreira G, Catheline G, Obeteen Consortium.   +9 more
europepmc   +1 more source