Results 71 to 80 of about 2,620,157 (317)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Tacrolimus as an adjunct to autologous minced muscle grafts for the repair of a volumetric muscle loss injury

open access: yesJournal of Experimental Orthopaedics, 2017
Background Volumetric muscle loss (VML) following extremity orthopaedic trauma or surgery results in chronic functional deficits and disability. A current translational approach to address the devastating functional limitations due to VML injury is the ...
Benjamin T. Corona   +3 more
doaj   +1 more source

L’ingénierie curriculaire en langue française : le modèle de transposition didactique en débat

open access: yesMultilinguales, 2020
The concept of didactic transposition, linked to the notion of scholarly knowledge, needs to be broadened so as to meet the requirements to import to school things to be taught which are not referred to academic knowledge but to linguistic practices ...
Mansour Chemkhi
doaj   +1 more source

LINGUISTIC AND CULTURAL STUDIES IN CLASSES OF GERMAN [PDF]

open access: yesВісник Університету імені Альфреда Нобеля. Серія Педагогіка і психология, 2019
Linguistic and cultural studies are an integral part of learning a foreign language. Language cannot be studied without learning culture, history, geography, traditions, people’s preferences in food, clothing and their behaviour.
Olena Beresten
doaj   +1 more source

Return to Flight Task Group [PDF]

open access: yes, 2003
On June 13, 2003 the NASA Administrator appointed two vetereran astronauts to lead an external task group in an independent assessment of the agency's "Return to Flight" efforts and to help the nation return the Space Shuttle safely to flight. On August
Return to Flight Task Group
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Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Material Collected From the Induced Seismicity State Task Force Meeting, Wednesday, April 16, 2014, Newman University, Wichita, Kansas [PDF]

open access: yes, 2014
Announcement -- Agenda -- Breakout Sessions: Questions and Responses -- An Ounce of Understanding is Worth a Pound of Cure / by Kyle E. Murray -- Induced Seismicity and the Oil and Gas Industry -- Overview of Kansas Earthquakes / Rick Miller, Shelby ...
Induced Seismicity State Task Force Meeting (2014 : Wichita, Kan.)
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Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Final report of the Task Force on Sexual Preference [PDF]

open access: yes, 1978
At head of title: State of Oregon, Department of Human Resources.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

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