Results 71 to 80 of about 3,142,121 (258)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The task of the speaker and the task of the hearer [PDF]
Behavioral and Brain Sciences, 1987 Commentary on D. Sperber & D.
openaire +2 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Online Learning Task Force report
, 2009 Title from PDF cover (viewed on January 31, 2020)."Senate Bill 767 (2009) established the Online Learning Task Force to craft a thoughtful policy for online learning in Oregon"--Page 1.This archived document is maintained by the State Library of Oregon ...
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New Jersey Mercury Task Force Report, Volume II: Exposures and Impacts
, 2002 The New Jersey Mercury Task Force was directed to complete the following tasks: 1. Review the current science on: a) impacts of mercury pollution on public health and ecosystems; and b) mercury deposition, transport, and exposure pathways. 2. Inventory
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on October 28, 2014)"Draft ...
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, 2003 On June 13, 2003 the NASA Administrator appointed two vetereran astronauts to lead an external task group in an independent assessment of the agency's "Return to Flight" efforts and to help the nation return the Space Shuttle safely to flight. On August
Return to Flight Task Group
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source