Results 101 to 110 of about 1,802,298 (288)

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas   +39 more
wiley   +1 more source

Elevated temperature enhances task performance by improving cognitive abilities in common rudd (Scardinius erythrophthalmus)

open access: yesScientific Reports
The thermal sensitivity of task performance in ectothermic organisms may depend on how temperature affects mobility, cognitive ability, or their interaction. Furthermore, these processes may vary with experience or task difficulty.
Monika Sysiak   +6 more
doaj   +1 more source

Stochastic Tasks: Difficulty and Levin Search

open access: yes, 2015
We establish a setting for asynchronous stochastic tasks that account for episodes, rewards and responses, and, most especially, the computational complexity of the algorithm behind an agent solving a task. This is used to determine the difficulty of a task as the (logarithm of the) number of computational steps required to acquire an acceptable policy
openaire   +3 more sources

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source

Task difficulty modulates motor learning benefits of balance exercises in community-dwelling older adults

open access: yesExperimental Gerontology
Purpose: Balance disorders are a major modifiable risk factor for falls, and balance exercises reduce fall rates. However, the effectiveness of balance exercises may depend on the relationship between the task difficulty and individual skill levels. This
Kazunori Akizuki   +5 more
doaj   +1 more source

An Integrated Framework for AI Assisted Level Design in 2D Platformers

open access: yes, 2018
The design of video game levels is a complex and critical task. Levels need to elicit fun and challenge while avoiding frustration at all costs. In this paper, we present a framework to assist designers in the creation of levels for 2D platformers.
Aramini, Antonio Umberto   +2 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Multidimensional approach of objective difficulty in an aiming task

open access: yesEuropean Journal of Human Movement, 2010
This article deals with a new method to classify informational motor tasks, through a multidimensional approach of difficulty. The following experiment is used: 345 subjects are asked to point at computer-managed mobile targets.
P. Genty   +3 more
doaj  

Effects of Task Complexity, Task Conditions, and Task Difficulty on the Grammatical Accuracy of EFL Learners in Written Discourse [PDF]

open access: yesJournal of Applied Linguistics, 2012
Different methods of language teaching have tried to help EFL learners to develop good language skills based on their various perspectives. Research findings have underscored the effect of using task types in promoting language skills in terms of ...
Saeideh Ahangari, Mahlagha Akbari
doaj  

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

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