Results 111 to 120 of about 4,495,422 (287)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Large language model-based embodied intelligence task planning: from single-agent to multi-agent

大数据
With the development of artificial intelligence, embodied intelligence and task planning have gradually become research hotspots. Traditional task planning methods lack flexibility when facing unpredictable environments, while large language models, with
JIA Ziqi, WANG Jianzong, ZHANG Xulong, QU Xiaoyang   +3 more
doaj   +2 more sources

Unpacking response inhibition in animals – part 1: a conceptual framework

Animal Cognition
Response inhibition - the ability to suppress or stop actions - is crucial for adaptive behaviour across species. The concept of response inhibition has traditionally been regarded as a unidimensional psychological ability.
Camille A. Troisi, Alizée Vernouillet, Reinoud Allaert, Sophia Knoch, An Martel, Luc Lens, Frederick Verbruggen   +6 more
doaj   +1 more source

YOLO POD: a fast and accurate multi-task model for dense Soybean Pod counting. [PDF]

Plant Methods, 2023
Xiang S, Wang S, Xu M, Wang W, Liu W.
europepmc   +1 more source

Prediction of pilot reserve attention capacity during air-to-air target tracking [PDF]

Reserve attention capacity of a pilot was calculated using a pilot model that allocates exclusive model attention according to the ranking of task urgency functions whose variables are tracking error and error rate. The modeled task consisted of tracking
Faulkner, W. H., Onstott, E. D.
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Joint Vestibular Schwannoma Enlargement Prediction and Segmentation Using a Deep Multi-task Model. [PDF]

Laryngoscope, 2023
Wang K, George-Jones NA, Chen L, Hunter JB, Wang J.   +4 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Task model-specific operator skill assessment in routine fetal ultrasound scanning. [PDF]

Int J Comput Assist Radiol Surg, 2022
Wang Y, Yang Q, Drukker L, Papageorghiou A, Hu Y, Noble JA.   +5 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source