Results 121 to 130 of about 4,495,422 (287)
Вестник Российского экономического университета имени Г. В. ПлехановаThe article provides a mathematic model of assessing the potential of import substitution at big industrial enterprises and in branches of production. The practical use of the model is carried out in conditions of Russian highly technological enterprise ...
T. A. Berkutova +2 more
doaj +1 more source
, 2012 The Comenius Network Project “Developing Quality in Mathematics Education II” funded by the European Commission consists of partners from schools, universities and teacher training centres from eleven European countries. One advantage of the project is the mutual exchange between teachers, teacher trainers and researchers in developing learning ...
openaire +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The efficacy of a task model approach to ADL rehabilitation in stroke apraxia and action disorganisation syndrome: A randomised controlled trial. [PDF]
PLoS One, 2022 Howe J +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Multi-Task Model for Esophageal Lesion Analysis Using Endoscopic Images: Classification with Image Retrieval and Segmentation with Attention. [PDF]
Sensors (Basel), 2021 Yu X, Tang S, Cheang CF, Yu HH, Choi IC.
europepmc +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Spectral bias and task-model alignment explain generalization in kernel regression and infinitely wide neural networks. [PDF]
Nat Commun, 2021 Canatar A, Bordelon B, Pehlevan C.
europepmc +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source