Results 141 to 150 of about 2,689,429 (376)

The Diverse Neuromuscular Spectrum of VPS13A Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger, Evamaria Riedel, Marie Hackenberg, Alexander Mensch, Stefanie Beck‐Woedl, Joohyun Park, Tobias B. Haack, Bernhard Haslinger, Jan Kirschke, Holger Prokisch, Andreas Hermann, Christian Mawrin, Adrian Danek, Benedikt Schoser, Kevin Peikert, Marcus Deschauer, Isabell Cordts   +16 more
wiley   +1 more source

Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco, Mònica Roldán, Yalda Jamshidi, Ioannis Georvasilis, Rocío Jadraque Rodríguez, Reza Boostani, Ali Shoeibi, Lluís Armengol, Anna Codina, Ehsan Ghayoor Karimiani, Cristina Hernando‐Davalillo, Loreto Martorell, María Luisa Ramírez Almaraz, Jordi Muchart, Carlos Ortez, Andrés Nascimento, Roser Urreizti, Daniel Natera‐de Benito, Mercedes Serrano   +18 more
wiley   +1 more source

A FUNCTIONAL SKETCH FOR RESOURCES MANAGEMENT IN COLLABORATIVE SYSTEMS FOR BUSINESS [PDF]

This paper presents a functional design sketch for the resource management module of a highly scalable collaborative system. Small and medium enterprises require such tools in order to benefit from and develop innovative business ideas and technologies ...
Moca Mircea, Silaghi Gheorghe Cosmin
core  

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source

CURRENT STATUS OF PROJECT MANAGEMENT PROCESSES FOR ACADEMIC-COMMUNITY COLLEGE OF VENEZUELA IN COJEDES STATE, IN THE CONTEXT OF MUNICIPALIZATION / ESTADO ACTUAL DE LA DIRECCIÓN POR PROCESOS DEL PROYECTO ACADÉMICO-COMUNITARIO DE LA UNIVERSIDAD BOLIVARIANA DE VENEZUELA EN EL ESTADO COJEDES, EN EL CONTEXTO DE LA MUNICIPALIZACIÓN

Didasc@lia: didáctica y educación, 2013
The academic-community project of the Bolivarian University of Venezuela (UBV), represents an integrated core, where converge the theory and practice, to join the process of training, research and community interaction.
José Miguel Aular Quiroz, Rolando Borrero Rivero   +1 more
doaj  

PERSPECTIVES MANAGEMENT: AN ESSENTIAL TASK IN PROJECTS

, 1998
This study analyses management accounting and control projects in a change process context. What patterns of communication do project managers in management accounting and control projects develop? What are the consequences of these patterns?  Projects in three Swedish manufacturing companies are analysed in relation to previously published Swedish and
openaire   +1 more source

SISTEM PENGELOLAAN KEUANGAN PADA BADAN PERENCANAAN PEMBANGUNAN DAERAH KABUPATEN SEMARANG TAHUN 2015 [PDF]

, 2017
This final project discusses about how the financial management in Bappeda Semarang Regency. The background of the writing of this final task in terms of finance that has not tereaslisasi completely. Writing this final task using qualitative methods and
Regi, Nedia Marta
core  

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong, Shasha Yu, Jing Zhang, Yu Zu, Yujing Zhang, Jing Lv, Xuyang Cao, Xuedan Feng   +7 more
wiley   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

Synergizing Global and Local Strategies for Dynamic Project Management: An Advanced Machine Learning-Enhanced Framework

IEEE Access
In this study, we introduce a versatile and scalable optimization tool designed to address several critical project management needs. Our aim is to provide project managers with a robust decision support system that enhances and streamlines decision ...
George Sklias, Socratis Gkelios, Dimitrios Dimitriou, Maria Sartzetaki, Savvas A. Chatzichristofis   +4 more
doaj   +1 more source