Results 231 to 240 of about 2,596,061 (361)

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

A reliable framework for supply chain management using cluster based blockchain for intelligent industrial automation. [PDF]

Sci Rep
Alsolami E, Al-Khasawenh MA, Alarood AA, Alzahrani AO, Ibraheem AA, Zamani M.   +5 more
europepmc   +1 more source

A Different Perspective on the Solid Lubrication Performance of Black Phosphorous: Friend or Foe?

Advanced Engineering Materials, EarlyView.
Researchers investigate black phosphorous (BP) as a standalone solid lubricant coating through ball‐on‐disc linear‐reciprocating sliding experiments in dry conditions. Testing on different metals shows BP doesn't universally reduce friction and wear. However, it achieves 33% friction reduction on rougher iron surfaces and 23% wear reduction on aluminum.
Matteo Vezzelli, Manel Rodríguez Ripoll, Sabine Schwarz, Ali Erdemir, Maria Clelia Righi, Carsten Gachot   +5 more
wiley   +1 more source

The use of implementation mapping in healthcare settings: a scoping review. [PDF]

Front Public Health
Warhurst K, Tyack Z, Beckmann M, Abell B.   +3 more
europepmc   +1 more source

Bistable Mechanisms 3D Printing for Mechanically Programmable Vibration Control

Advanced Engineering Materials, EarlyView.
This work introduces a 3D‐printed bistable mechanism integrated into tuned mass dampers (TMDs) for mechanically adaptive passive vibration suppression. Through optimized geometry, the bistable design provides adaptable vibration reduction across a broad range of scenarios, achieving effective vibration mitigation without complex controls or external ...
Ali Zolfagharian, Frédéric Demoly, Mohammad Lakhi, Bernard Rolfe, Mahdi Bodaghi   +4 more
wiley   +1 more source

Multi skill project scheduling optimization based on quality transmission and rework network reconstruction. [PDF]

Sci Rep
Peng J, Su Z, Liu X.
europepmc   +1 more source

The Tasks and Methods of the Organization's Maturity Level Increasing in the Field of Project Management

, 2018
D.Yu. Adamets, И. В. Буркова
openalex   +2 more sources

Femtosecond Single‐ and Double‐Pulse Fabrication of Periodic Nanostructures on Stainless Steel for Surface‐Enhanced Raman Spectroscopy

Advanced Engineering Materials, EarlyView.
Periodic submicron features are fabricated on 304 stainless steel using single and double femtosecond laser pulses. By adjusting polarization, fluence, and inter‐pulse delay, 1D and 2D nanostructures are formed. Enhanced hydrophobicity and dense surface‐enhanced Raman spectroscopy hotspots enable analyte detection down to 10−10 M with good ...
Balaji Baskar, Atiqul Islam Ahad, Carla Berrospe‐Rodriguez, Guillermo Aguilar   +3 more
wiley   +1 more source

Improving Workflow With a Task Buddy System in a Family Medicine Residency. [PDF]

PRiMER
Hawks K, Dahl B, Melkonian A, Helmly L.
europepmc   +1 more source

Quality Enhancement of Laser Powder‐Bed Fusion Parts by Acoustically Assisted Additive Manufacturing by Laser Powder‐Bed Fusion and its Application to Lattice Structures

Advanced Engineering Materials, EarlyView.
Additive manufacturing technologies like laser powder‐bed fusion offer great design freedom and individualization of products down to a batch size of one. However, parts fabricated with this technology suffer from poor quality. Acoustic assistance during the build process can minimize these drawbacks.
Oliver Maurer, Dirk Bähre
wiley   +1 more source