Results 41 to 50 of about 1,798,204 (306)

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

E-learning Aspects of NODES Project [PDF]

open access: yes, 2006
The NODES project aims at promoting the use, in adult training/lifelong learning, of multimedia knowledge, in order to facilitate competitiveness, employability and mobility of adults who are victims of the digital divide or of some of its components ...
Herdon, Miklós, Várallyai, László
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

The Problems of project management software implementation in construction corporations

open access: yesMATEC Web of Conferences, 2016
The article is devoted to the main problems facing many companies, implementing software project management activities have been working construction corporation.
Kagan Pavel, Naumova Anna, Vilman Yuriy
doaj   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

open access: yesMolecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo   +6 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Artificial intelligence and project management: An empirical investigation on the appropriation of generative Chatbots by project managers

open access: yesJournal of Innovation & Knowledge
The integration of generative AI tools, such as chatbots, into project management is revolutionizing the field. This paper explores how project managers are adopting and adapting these tools, specifically focusing on ChatGPT, for enhanced project ...
Alberto Michele Felicetti   +3 more
doaj   +1 more source

Pembuatan Aplikasi Desktop dan Nirkabel Via GPRS dengan Didukung Teknologi SMS untuk Sistem Perpustakaan GKI Taman Cibunut [PDF]

open access: yes, 2007
Most borrowing activity in library has the documentation for its borrowing that help library system. One of the library that writer took for his project was library system in one of the church in Bandung called GKI Taman Cibunut.
Christianti, M. (Meliana)   +1 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

A Quantitative Framework for Task Allocation in Distributed Agile Software Development

open access: yesIEEE Access, 2018
Distributed agile software development is a promising paradigm, addressing the necessities of emergent software application markets that are described by huge user base and small time to market characteristics.
Waqar Aslam, Farah Ijaz
doaj   +1 more source

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