Results 101 to 110 of about 103,882 (274)

Development of an implementation framework for task shifting and task sharing in Africa

open access: yes, 2023
, North-West University, Potchefstroom CampusAchieving universal health coverage (UHC) by 2030 is one of the targets (Target 3.8) of the United Nations Sustainable Development Goals.
Okoroafor, SC
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The effect of dual task demands and proficiency on second language speech production [PDF]

open access: yes, 2012
In this study we examined how the introduction of a parallel finger-tapping task influences second language speech (L2) encoding mechanisms and monitoring processes and how the level of proficiency impacts the efficiency and accuracy of L2 performance ...
Declerck, Mathieu, Kormos, Judit
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Spatial attention shifting and phonological processing in adults with dyslexia

open access: yes, 2015
According to Hari and Renvall’s (2001) sluggish attentional shifting (SAS) hypothesis people with dyslexia have a central deficit in attention shifting.
Larkin, RF, Abbott, I, Dunn, AK
core  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Assessing the Impact of Task-Shifting on Infant, Maternal and Child Health Outcomes in Rural Nigeria

open access: yesمجلة الكوفة الطبية
   By using a longitudinal panel data approach, this study assesses how task-shifting affects maternal, infant, and child health outcomes in underdeveloped Nigeria. An analysis was done of data from administrative health records, national health surveys,
Yusuf Adeniyi Jamiu   +2 more
doaj   +1 more source

Potential impact of task shifting on clinical labor costs.

open access: yes, 2016
Potential impact of task shifting on clinical labor costs.
Dayanund Loykissoonlal (560278)   +6 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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