Results 1 to 10 of about 238,676 (207)

Extracellular Vesicles as Promising Carriers in Drug Delivery: Considerations from a Cell Biologist’s Perspective

Biology, 2021
The use of extracellular vesicles as cell-free therapy is a promising approach currently investigated in several disease models. The intrinsic capacity of extracellular vesicles to encapsulate macromolecules within their lipid bilayer membrane-bound ...
Giona Pedrioli, Ester Piovesana, Elena Vacchi, Carolina Balbi   +3 more
doaj   +1 more source

Induction of the CD24 Surface Antigen in Primary Undifferentiated Human Adipose Progenitor Cells by the Hedgehog Signaling Pathway

Biologics, 2021
In the murine model system of adipogenesis, the CD24 cell surface protein represents a valuable marker to label undifferentiated adipose progenitor cells.
Francesco Muoio, Stefano Panella, Yves Harder, Tiziano Tallone   +3 more
doaj   +1 more source

Chemically Defined Xeno- and Serum-Free Cell Culture Medium to Grow Human Adipose Stem Cells

Cells, 2021
Adipose tissue is an abundant source of stem cells. However, liposuction cannot yield cell quantities sufficient for direct applications in regenerative medicine.
Stefano Panella, Francesco Muoio, Valentin Jossen, Yves Harder, Regine Eibl-Schindler, Tiziano Tallone   +5 more
doaj   +1 more source

Development of a Biodegradable Microcarrier for the Cultivation of Human Adipose Stem Cells (hASCs) with a Defined Xeno- and Serum-Free Medium

Applied Sciences, 2021
Stirred single-use bioreactors in combination with microcarriers (MCs) have established themselves as a technology that has the potential to meet the demands of current and future cell therapeutic markets.
Francesco Muoio, Stefano Panella, Matias Lindner, Valentin Jossen, Yves Harder, Tiziano Moccetti, Regine Eibl, Michele Müller, Tiziano Tallone   +8 more
doaj   +1 more source

Hijacking Endocytosis and Autophagy in Extracellular Vesicle Communication: Where the Inside Meets the Outside

Frontiers in Cell and Developmental Biology, 2021
Extracellular vesicles, phospholipid bilayer-membrane vesicles of cellular origin, are emerging as nanocarriers of biological information between cells. Extracellular vesicles transport virtually all biologically active macromolecules (e.g., nucleotides,
Giona Pedrioli, Giona Pedrioli, Paolo Paganetti, Paolo Paganetti   +3 more
doaj   +1 more source

Emerging Evidences for an Implication of the Neurodegeneration-Associated Protein TAU in Cancer

Brain Sciences, 2020
Neurodegenerative disorders and cancer may appear unrelated illnesses. Yet, epidemiologic studies indicate an inverse correlation between their respective incidences for specific cancers.
Stéphanie Papin, Paolo Paganetti
doaj   +1 more source

Human Adipose Stem Cells (hASCs) Grown on Biodegradable Microcarriers in Serum- and Xeno-Free Medium Preserve Their Undifferentiated Status

Journal of Functional Biomaterials, 2021
Human adipose stem cells (hASCs) are promising candidates for cell-based therapies, but they need to be efficiently expanded in vitro as they cannot be harvested in sufficient quantities.
Francesco Muoio, Stefano Panella, Valentin Jossen, Matias Lindner, Yves Harder, Michele Müller, Regine Eibl, Tiziano Tallone   +7 more
doaj   +1 more source

An Approach towards a GMP Compliant In-Vitro Expansion of Human Adipose Stem Cells for Autologous Therapies

Bioengineering, 2020
Human Adipose Tissue Stem Cells (hASCs) are a valuable source of cells for clinical applications (e.g., treatment of acute myocardial infarction and inflammatory diseases), especially in the field of regenerative medicine.
Valentin Jossen, Francesco Muoio, Stefano Panella, Yves Harder, Tiziano Tallone, Regine Eibl   +5 more
doaj   +1 more source

Keuzes en accenten

BMGN: Low Countries Historical Review, 2002
The author tries to assess the merits of Welvaart in zwart-wit [Affluence in black-and-white] by Kees Schuyt and Ed Taverne. He concludes that notwithstanding a certain lack of originality, Schuyt and Taverne have written a highly interesting and ...
D. Bosscher
doaj   +1 more source

Oscillatory Activity in the Cortex, Motor Thalamus and Nucleus Reticularis Thalami in Acute TTX and Chronic 6-OHDA Dopamine-Depleted Animals

Frontiers in Neurology, 2018
The motor thalamus (MTh) and the nucleus reticularis thalami (NRT) have been largely neglected in Parkinson's disease (PD) research, despite their key role as interface between basal ganglia (BG) and cortex (Cx). In the present study, we investigated the
Laura C. Grandi, Alain Kaelin-Lang, Alain Kaelin-Lang, Alain Kaelin-Lang, Gergely Orban, Wei Song, Agnese Salvadè, Alessandro Stefani, Giuseppe Di Giovanni, Giuseppe Di Giovanni, Salvatore Galati   +10 more
doaj   +1 more source