Results 91 to 100 of about 1,055,208 (296)
The Final Ascent: from refuges to ruins in a warming world [PDF]
Research Ideas and OutcomesMountains exemplify how climate change transforms long-standing refuges into zones of loss. As species track suitable climates upslope, they confront absolute ecological limits.
Dominic Wanke, Daniel Whitmore
doaj +3 more sources
Echinocereus pensilis updated [PDF]
, 2018 The taxonomy of the unique Echinocereus pensilis is updated based on recent molecular evidence that supports the 1974 reassessment of this species as meriting its one genus. Hence the most appropriate current taxonomy is for a monospecific genus with the
Walker, Colin C.
core
MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts
Advanced Science, EarlyView.We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang +5 more
wiley +1 more source
Advanced Science, EarlyView.Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li +8 more
wiley +1 more source
Advanced Science, EarlyView.This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing +10 more
wiley +1 more source
A Taxonomy of model-based testing [PDF]
, 2006 Model-based testing relies on models of a system under test and/or its environment to derive test cases for the system. This paper provides an overview of the field.
Legeard, Bruno +2 more
core
Advanced Science, EarlyView.This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia +5 more
wiley +1 more source
A taxonomy of cyber risk taxonomies
Risk AnalysisAbstractThe field of cyber risks is rapidly expanding, yet significant research remains to be conducted. Numerous taxonomy‐based systems have been proposed in both the academic literature and industrial practice to classify cyber risk threats. However, the fragmentation of various approaches has resulted in a plethora of taxonomies, often incongruent ...
Rabitti G. +3 more
openaire +3 more sources
Advanced Science, EarlyView.A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil +7 more
wiley +1 more source