Results 101 to 110 of about 1,196,822 (348)

Content and services issues for digital libraries [PDF]

open access: yes, 2004
Describes the neglected area of e-collection building, on the taxonomy of e-collections and on the possible range of online ...
Law, Derek
core  

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

open access: yesAdvanced Science, EarlyView.
The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang   +22 more
wiley   +1 more source

A taxonomy of cyber risk taxonomies

open access: yesRisk Analysis
AbstractThe field of cyber risks is rapidly expanding, yet significant research remains to be conducted. Numerous taxonomy‐based systems have been proposed in both the academic literature and industrial practice to classify cyber risk threats. However, the fragmentation of various approaches has resulted in a plethora of taxonomies, often incongruent ...
Rabitti G.   +3 more
openaire   +3 more sources

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

open access: yesAdvanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su   +15 more
wiley   +1 more source

Chasmophyte Cymbalaria muralis (Plantaginaceae), a new distribution record for Kashmir Himalaya

open access: yesDiscover Plants
Cymbalaria muralis G.Gaertn., B.Mey. & Scherb., Ivy-leaved toadflax a creeping perennial herb native to southern and central Europe, is reported for the first time from the Kashmir Himalaya.
Anzar Ahmad Khuroo   +2 more
doaj   +1 more source

Coating of microscope slide labels: a possible solution for their long-term preservation [PDF]

open access: yesNatural History Collections and Museomics
Microscope slide labels hold valuable scientific information within natural history collections, making their long-term preservation crucial. This study tests Paraloid B-72 as a potential protective coating, offering a quick and simple method to ...
Simon Müller   +4 more
doaj   +3 more sources

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

open access: yesAdvanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo   +3 more
wiley   +1 more source

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

open access: yesAdvanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun   +14 more
wiley   +1 more source

A Taxonomy of model-based testing [PDF]

open access: yes, 2006
Model-based testing relies on models of a system under test and/or its environment to derive test cases for the system. This paper provides an overview of the field.
Legeard, Bruno   +2 more
core  

Home - About - Disclaimer - Privacy