Results 91 to 100 of about 346,397 (348)
Advanced Science, EarlyView.BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang +9 more
wiley +1 more source
Varieties of Exploratory Experimentation in Nanotoxicology [PDF]
, 2008 There has been relatively little effort to provide a systematic overview of different forms of exploratory experimentation (EE). The present paper examines the growing subdiscipline of nanotoxicology and suggests that it illustrates at least four ways ...
Elliott, Kevin
core
Advanced Science, EarlyView.A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu +6 more
wiley +1 more source
How do I enhance motivation to learn and higher order cognition among students of Science through the use of a virtual learning environment? [PDF]
, 2010 In this paper I explore the capacity of Moodle to enhance the teaching and learning of Leaving Certificate Biology within a small urban secondary school.
McMahon, Mary
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Editorial: Microbial Taxonomy, Phylogeny and Biodiversity [PDF]
, 2019 The great diversity of microbial life is the remaining majorreservoir of unknown biologicaldiversity on Earth. To understand this vast, but largely unperceived diversity with its untappedgenetic, enzymatic and industrial potential, microbial systematics ...
Balboa, Sabela +2 more
core +2 more sources
Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors
Advanced Science, EarlyView.This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su +15 more
wiley +1 more source
Scientific Knowledge in Aristotle’s Biology [PDF]
, 2015 Aristotle was the first thinker to articulate a taxonomy of scientific knowledge, which he set out in Posterior Analytics. Furthermore, the “special sciences”, i.e., biology, zoology and the natural sciences in general, originated with Aristotle.
Botter, Barbara
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The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
Advanced Science, EarlyView.The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
The Mental Lives of Sheep and the Quest for a Psychological Taxonomy [PDF]
, 2019 In this commentary on Marino and Merskin's "Intelligence, complexity, and individuality in sheep", I argue that their literature review provides further evidence of the fundamental theoretical shift in psychology towards a non-anthropocentric ...
Figdor, Carrie
core +2 more sources