Results 111 to 120 of about 340,452 (356)
Advanced Science, EarlyView.REEP1 contributes to endoplasmic reticulum (ER) shaping. Variants either cause cortical motoneuron degeneration and hereditary spastic paraplegia (HSP) or spinal motoneuron degeneration and distal hereditary motor neuropathy (dHMN). Knockout causes less complex ER structures and cortical motoneuron loss.
Andrea Bock +25 more
wiley +1 more source
Diversity and Ecological Potentials of Marine Viruses Inhabiting Continental Shelf Seas
Advanced Science, EarlyView.To the best of the knowledge, this study provides the largest viral genome dataset from a continental shelf sea. It reveals that over half of vOTUs are novel, highlighting the remarkable viral novelty in the eastern continental shelf seas of China (ECSSC).
Xiaoyue Guo +9 more
wiley +1 more source
Identification of Birds through DNA Barcodes [PDF]
, 2004 Short DNA sequences from a standardized region of the genome provide a DNA barcode for identifying species. Compiling a public library of DNA barcodes linked to named specimens could provide a new master key for identifying species, one whose power will ...
+58 more
core +7 more sources
Advanced Science, EarlyView.The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang +22 more
wiley +1 more source
ETHNOMEDICINAL SURVEY OF PLANTS IN PROTECTED AREAS OF KASHMIR HIMALAYA: A CASE STUDY OF THE HIRPORA WILDLIFE SANCTUARY [PDF]
Exploratory Animal and Medical Research: In remote Himalayan regions, ethnic communities living near protected areas are dependent on medicinal plants for their healthcare. Although several studies related to ethnomedicine are available from Kashmir Himalaya, however studies focusing on ...
Mohd Suliman Dar +5 more
doaj +1 more source
Chronic PET‐Microplastic Exposure: Disruption of Gut–Liver Homeostasis and Risk of Hepatic Steatosis
Advanced Science, EarlyView.Chronic exposure to environmentally relevant PET microplastics disrupts gut–liver homeostasis, leading to hepatic steatosis, early fibrosis, and altered gut microbiota. These effects signal metabolic imbalance and gut–liver axis impairment, emphasizing chronic microplastic ingestion as an emerging environmental health risk linked to non‐communicable ...
Surye Park +5 more
wiley +1 more source
How do I enhance motivation to learn and higher order cognition among students of Science through the use of a virtual learning environment? [PDF]
, 2010 In this paper I explore the capacity of Moodle to enhance the teaching and learning of Leaving Certificate Biology within a small urban secondary school.
McMahon, Mary
core
Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors
Advanced Science, EarlyView.This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su +15 more
wiley +1 more source
Taxonomy, systematics and ecology of the phylum Tardigrada [PDF]
, 2014 This thesis is based on published papers, however there have been issues encountered with copyright permissions, therefore a fuller version may be submitted in the future.I conducted a series of research programmes on various aspects of Tardigrada ...
Marley, Nigel
core +1 more source