Results 131 to 140 of about 39,590 (250)

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Orchestrating faster access to products of non-profit R&D: a case study of a novel regimen for drug-resistant tuberculosis. [PDF]

BMJ Glob Health
Moon S, Vieira MCF, Large K.
europepmc   +1 more source

Head‐to‐Head Comparison of Four Ultrasound Elastography Techniques in Detecting Advanced Fibrosis

Portal Hypertension &Cirrhosis, EarlyView.
Elastography is an important noninvasive method for diagnosing advanced fibrosis (AF); however, evidence remains insufficient, particularly regarding acoustic radiation force impulse (ARFI) techniques. This prospective mulitcenter study concludes that vibration controlled transient elastography (VCTE) demonstrates superior diagnostic performance to ...
Jiahao Han, Lichen Chu, Lixin Yang, Kexin Lou, Guangbin Dou, Huiming Shen, Xiaojun Cheng, Zuowei Bao, Jia Li   +8 more
wiley   +1 more source

Dissecting the Chemical and Thermal Stabilities of Tetrads in G-Quadruplexes to Derive a Structure-Activity Relation for a Thrombin-Binding DNA G-Quadruplex Aptamer. [PDF]

Chembiochem
Wirmer-Bartoschek J, Ferner JP, Heckel A, Schwalbe H.   +3 more
europepmc   +1 more source

Soybean induced resistance to Spodoptera eridania herbivory

Pest Management Science, EarlyView.
SOD, CAT, APX, PPO, KTI, and MDA levels were higher in the resistant soybean. S. eridania herbivory increased H2O2 and MDA, but decreased SOD and PPO levels. S. eridania herbivory increased KTI activity only in the resistant variety. Isoquercitrin and daidzin were exclusive to resistant and susceptible soybeans.
Bruno Henrique Sardinha de Souza, Arlindo Leal Boiça Júnior, Durvalina Maria Mathias dos Santos, Moacir Rossi Forim, Antonio Pizolato Neto, Andreísa Fabri Lima, Michael Joseph Stout   +6 more
wiley   +1 more source

A Biomimetic Electrochemical Approach for Chlorogenic Acid Detection in Herbal Supplements and Plant Extracts Using Molecular Imprinting Technology. [PDF]

ACS Omega
Yayla S, Cetinkaya A, Kocak E, Nemutlu E, Hurkul MM, Ozkan SA.   +5 more
europepmc   +1 more source

Machine learning‐driven advances in carbon‐based quantum dots: Opportunities accompanied by challenges

Responsive Materials, EarlyView.
Machine learning provides a unifying framework to connect structure, fluorescence properties, and applications of carbon‐based quantum dots. This review highlights how data‐driven strategies enable fluorescence regulation, reveal underlying mechanisms, and accelerate the rational design of functional carbon dots.
Liangfeng Chen, Siwei Yang, Xiangqian Cui, Ziheng Liu, Hang Wang, Yongqiang Li, Peng He, Miao Wang, Guqiao Ding   +8 more
wiley   +1 more source

External mechanical force drives axonal cytoskeletal rearrangements. [PDF]

Curr Biol
Swaim GL, Glomb OV, Xie Y, Emerson C, Li Z, Beaudet D, Hendricks AG, Yogev S.   +7 more
europepmc   +1 more source

Small‐Scale Magnetic Soft Robots for Medical Applications: From Laboratory to Clinical Use

SmartBot, EarlyView.
Small‐scale magnetic soft robots are emerging as promising platforms for minimally invasive diagnosis and therapy in complex in vivo environments. This review compares untethered and tethered medical magnetic robots in parallel across five translational stages, from basic performance testing to clinical evaluation.
Xingxing Ke, Shizhi Li, Tianrui Zhang, Yue Zhong, Songyang Li, Shuo Zhang, Zhiping Chai, Menghao Pu, Zisheng Zong, Haochen Yong, Xingxing Dong, Lanting Huang, Zhen Deng, Shuaizheng Yan, Yue Zhang, Zhaoju Zhu, Mingzhu Zhu, Linze Li, Ruiquan Chen, Shu Zhang, Chong Wu, Di Wu, Lei Yang, Rui Chen, Tongzhi Niu, Hongling Qin, Han Ding, Bingwei He, Siqi Wu, Zhigang Wu   +29 more
wiley   +1 more source

Lanthanide-Centered Polyoxoalkoxide Complexes Provide a Platform for Systematic Room- and Variable-Temperature Nuclear Magnetic Resonance Studies. [PDF]

Inorg Chem
Shiels D, Gunarathna N, Brennessel WW, Matson EM.   +3 more
europepmc   +1 more source