Results 51 to 60 of about 66,805 (203)

Recent Neutrino Data and Type III Seesaw with Discrete Symmetry

open access: yes, 2012
In light of the recent neutrino experiment results from Daya Bay and RENO Collaborations, we study phenomenology of neutrino mixing angles in the Type III seesaw model with an discrete $A_4 \times Z_2$ symmetry, whose spontaneously breaking scale is much
Ahn, Y. H., Kim, C. S., Oh, Sechul
core   +1 more source

Assessing transporter‐mediated rifampin–linezolid interaction using physiologically‐based pharmacokinetic modelling

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen   +4 more
wiley   +1 more source

Rh‐Catalyzed [2 + 2 + 2] Cycloaddition of Linked Bis(Diynes) Ar‐C≡C‐C≡C‐(CH2)3‐C≡C‐C≡C‐Ar With Quinones: Synthesis and Photophysical Properties of Bis(Arylethynyl)‐Naphthoquinones and Anthraquinones

open access: yesChemistry – A European Journal, EarlyView.
We report the synthesis bis(arylethynyl)naphtho‐ and anthraquinones via Rh(I)‐catalyzed [2 + 2 + 2] cycloaddition reactions. The substrate scope of both quinones and linked bis‐diynes was explored. Microwave irradiation remarkably enhanced yields.
Luana A. Machado   +16 more
wiley   +1 more source

Tuberculous meningitis is associated with higher cerebrospinal HIV-1 viral loads compared to other HIV-1-associated meningitides. [PDF]

open access: yesPLoS ONE, 2018
To gain a better understanding of the immunopathogenesis of tuberculous meningitis (TBM) and identify potential diagnostic biomarkers that may discriminate TBM from other HIV-1-associated meningitides, we assessed HIV-1 viral load levels, drug resistance
Ikanyeng D Seipone   +7 more
doaj   +1 more source

Perturbing exactly tri-bimaximal neutrino mixings with charged lepton mass matrices

open access: yes, 2011
We study perturbations of exactly tri-bimaximal neutrino mixings under the assumption that they are coming solely from the charged lepton mass matrix.
Adhikary   +133 more
core   +1 more source

Probing minimal supergravity in the type-I seesaw mechanism with lepton flavour violation at the CERN LHC [PDF]

open access: yes, 2008
The most general supersymmetric seesaw mechanism has too many parameters to be predictive and thus can not be excluded by any measurements of lepton flavour violating (LFV) processes.
A. Villanova del Moral   +7 more
core   +2 more sources

Investigation of the failure characteristics of fissure tunnels under dynamic and static combinations

open access: yesDeep Underground Science and Engineering, EarlyView.
This article aims to investigate the dynamic fracture response of fractured tunnel models under zero geological stress through physical experiments and numerical simulations. It further simulates the dynamic fracture characteristics of fractured tunnel models under geological stress ranging from 0 to 2.5 MPa using the numerical software AUTODYN ...
Peng Ying   +7 more
wiley   +1 more source

پیش‌بینی سرعت نفوذ TBM در حفاری سنگ سخت با استفاده از مدل NTH (مطالعه موردی تونل انتقال آب قمرود) [PDF]

open access: yesنشریه مهندسی معدن, 2006
حفاری مکانیزه تمام مقطع تونل‌ها توسط ماشین، دارای تاریخچه‌ای نزدیک به پنجاه سال می‌باشد. بررسی عملکرد، بخش مهمی از هر پروژه حفر تونل بوده و می‌تواند نقش اساسی در انتخاب روش و ماشین حفاری داشته باشد.
مرتضی احمدی   +2 more
doaj  

Failure characteristics and the energy criterion of rock with a through‐going joint under true‐triaxial unloading conditions: Insights from the DEM model

open access: yesDeep Underground Science and Engineering, EarlyView.
The rock failure mode is significantly influenced by the contributing factors, such as the joint inclination, the initial confining pressure, and the unloading point. We found six typical rock failure modes after a large number of numerical tests. Abstract Excavation unloading damages rock masses, with preferential failure along geological defects in ...
Fei Liu   +4 more
wiley   +1 more source

Deciphering Genetic Susceptibility to Tuberculous Meningitis

open access: yesFrontiers in Neurology, 2022
Tuberculous meningitis (TBM) is the most severe form of extrapulmonary tuberculosis (TB) that arises when a caseating meningeal granuloma discharges its contents into the subarachnoid space.
Haiko Schurz   +12 more
doaj   +1 more source

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