Results 241 to 250 of about 214,405 (338)

TCGA Pan-Cancer sample, expression, and mutation data for Project Cognoma

open access: gold, 2017
Daniel Himmelstein   +4 more
openalex   +2 more sources

The Expression and Prognostic Significance of the Nicotinic Receptor Cluster on 15q25 about CHRNA5 and PSMA4 mRNA in Lung Adenocarcinoma Utilizing TCGA Datasets [PDF]

open access: green, 2019
Yuxiu Wang   +9 more
openalex   +1 more source

CircLRBA Promotes Epithelial‐Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1

open access: yesAdvanced Science, EarlyView.
CircLRBA is highly expressed in breast cancer (BC) and associated with poor overall survival. Zeb1 mediated circLRBA facilitates BC cell proliferation, invasion, docetaxel (DTX) resistance and inhibits the infiltration of CD8+ T cell. CircLRBA could combine with SPOP to suppress the Twist1 ubiquitination degradation and enhances PD‐L1 transcription ...
Xiaosong Wang   +8 more
wiley   +1 more source

Transfer Learning and Permutation‐Invariance Improving Predicting Genome‐Wide, Cell‐Specific and Directional Interventions Effects of Complex Systems

open access: yesAdvanced Science, EarlyView.
SETComp, a transfer learning model based on permutation‐invariance, is pre‐trained on single‐compound intervention data and fine‐tuned on complex system (e.g., natural products) data. The model achieves up to 93.86% accuracy on complex system‐cell‐gene association predictions, outperforming the baseline by up to 27.59%.
Boyang Wang   +4 more
wiley   +1 more source

Mining TCGA database for prognostic genes in head and neck squamous cell carcinoma microenvironment [PDF]

open access: green, 2019
Qiuchi Ran   +5 more
openalex   +1 more source

An exploratory study on the potential of angiogenic genes in early HNSCC detection. [PDF]

open access: yesDiscov Oncol
Huang ML   +9 more
europepmc   +1 more source

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

open access: yesAdvanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour   +14 more
wiley   +1 more source

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