Results 251 to 260 of about 214,405 (338)

The correlation of DPM1 overexpression with immune infiltration and poor prognosis in hepatocellular carcinoma. [PDF]

Discov Oncol
You L, Zhou Y, Cheng Y, Wang H, Li H, Guo J.   +5 more
europepmc   +1 more source

A Distributed Classifier for MicroRNA Target Prediction with Validation Through TCGA Expression Data

, 2018
Asish Ghoshal, Jinyi Zhang, Michael A. Roth, Kevin Xia, Ananth Grama, Somali Chaterji   +5 more
openalex   +1 more source

ERβ/circAHNAK Axis Inhibits USP10–FMR1 Deubiquitination to Prevent m⁶A‐Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma

Advanced Science, EarlyView.
In clear cell renal cell carcinoma, estrogen receptor β (ERβ) upregulates circAHNAK, which competitively binds USP10 to prevent FMR1 deubiquitination, leading to FMR1 degradation. Loss of FMR1 hinders m⁶A‐dependent decay of ADAM17 mRNA, resulting in ADAM17 accumulation in tumor exosomes and enhanced angiogenesis.
Chao Xu, Sujing Zhang, Yuepeng Liu, Jingwei Lv, Yilong Cao, Yao Chen, Hao Sun, Bowei Zhang, Shengtao Dai, Jiehan Li, Xiaoling Li, Bei Shi, Qingyun Sun, Meng Zhu, Junfei Gu   +14 more
wiley   +1 more source

Constructing a Model Using Clock-Related lncRNAs for Predicting the Tumor Microenvironment of Gliomas. [PDF]

Brain Behav
Gong M, Sun C, Shi Z, Wang J, Zhai W, Yu Z.   +5 more
europepmc   +1 more source

Genomic and molecular landscape of DNA damage repair deficiency across The Cancer Genome Atlas [PDF]

, 2018
Bailey, Matthew H, Ding, Li, et al,
core   +1 more source

Tcga Filtered Dataset Used In Drivermaps Paper

, 2018
Siming Zhao
openalex   +2 more sources

DCAF12 Ubiquitin Ligase Promotes Lung Cancer Metastasis by Modulating the TRiC/CCT Chaperonin Complex

Advanced Science, EarlyView.
This study elucidates how DCAF12 facilitates non‐degradative ubiquitination to stabilize TRiC/CCT, thereby enhancing the folding capacity of chaperonins. This mechanism promotes the maturation of cytoskeletal proteins and activates key oncogenic drivers, including YAP, STAT3, and mTOR, ultimately driving metastatic progression in lung cancer.
Zhenyi Wang, Huanhuan Huang, Kaizong Huang, Xiaowen Cui, Leilei Wu, Renyu Lin, Zhe Zhao, Hua Chen, Cheng Zheng, Weilin Jin, Song Chen, Jiayan Chen, Yaping Xu, Dongping Wei   +13 more
wiley   +1 more source

Functional characterization of dysregulated LncRNAs in BRCA and CESC highlights their role in cancer prognosis. [PDF]

Sci Rep
Sharma M, Chourasia N, Priyanka P, Sarkar DP, Nag A, Saxena S.   +5 more
europepmc   +1 more source

Nutritional c‐Fos Induction Rewires Hepatic Metabolism and Can Promote Obesity‐Associated Hepatocellular Carcinoma

Advanced Science, EarlyView.
It is shown that hepatic c‐Fos responds to feeding, altering de novo lipogenesis, glycolysis, and a wide range of steatosis‐associated metabolic signaling pathways. Obesogenic diets cause hepatic c‐Fos overexpression, insulin resistance, and the induction of metabolic reprogramming‐related genes.
Ao Li, Eduardo H. Gilglioni, Wadsen St‐Pierre‐Wijckmans, Leila Hosseinzadeh, Christelle Veyrat‐Durebex, Sumeet Pal Singh, Roberto Coppari, Latifa Bakiri, Esteban N. Gurzov   +8 more
wiley   +1 more source

HONeYBEE: enabling scalable multimodal AI in oncology through foundation model-driven embeddings. [PDF]

NPJ Digit Med
Tripathi A, Waqas A, Schabath MB, Yilmaz Y, Rasool G.   +4 more
europepmc   +1 more source