Results 241 to 250 of about 61,833 (306)

Effectiveness of an Intervention to Improve Guideline-Directed Medications for Patients With Acute Heart Failure: A Randomized Clinical Trial. [PDF]

open access: yesJ Am Heart Assoc
Son JW   +19 more
europepmc   +1 more source

Synthesis of Microbial‐Derived Octadecanoids

open access: yesLipids, EarlyView.
C18‐carbon containing dietary polyunsaturated fatty acids (e.g., linoleic acid, α‐linolenic acid, and γ‐linolenic acid) are metabolized by bacteria in the gut into oxygenated lipid mediators termed octadecanoids. To study the biological function of these compounds, we report here the chemical synthesis of multiple octadecanoids.
Johanna Revol‐Cavalier   +6 more
wiley   +1 more source

Thiolate Salt Mediated Dynamic Silyl Ether Exchanges for Polymer Network Design and Deconstruction

open access: yesMacromolecular Rapid Communications, EarlyView.
This work introduces thiolate salts as mediators for dynamic silyl ether exchange. This platform enables the synthesis of reprocessable covalent adaptable polymer networks (CANs) and allows for sterically controlled, and tunable deconstruction of silyl ether‐containing thermosets.
Pierce T. Bombard   +9 more
wiley   +1 more source

NMR‐Based Structural Elucidation of a New Dihydroisocoumarin and Related Polyketides From a Mangrove‐Derived Fusarium sp.

open access: yesMagnetic Resonance in Chemistry, EarlyView.
Integration of bioactivity screening and LC–MS/MS metabolomics enabled the discovery of a new antibacterial dihydroisocoumarin from Fusarium sp. IQ‐1921. NMR‐based structural elucidation identified five related metabolites, with the new compound 1 showing the broadest activity against multidrug‐resistant bacteria. ABSTRACT Antimicrobial resistance (AMR)
Evelyn García‐Oceguera   +4 more
wiley   +1 more source

Prevention of commercial tobacco use among Native American youth. [PDF]

open access: yesFront Public Health
Wimbish-Tompkins R   +3 more
europepmc   +1 more source

Influence of THF as Internal‐Donor on Ziegler‐Natta Polyethylene Catalysts

open access: yesMacromolecular Reaction Engineering, EarlyView.
Ziegler–Natta catalysts remain widely applied due to robustness, handling ease, and cost‐effectiveness. To support further optimization, we examine how internal donors such as tetrahydrofuran influence catalyst performance and polymer characteristics.
Alexander Mottl   +7 more
wiley   +1 more source

Patient iPSC‐derived astrocytes reveal impaired homeostasis and reactive‐like features in propionic acidemia

open access: yesThe Journal of Pathology, EarlyView.
Abstract Propionic acidemia (PA) is a neurometabolic disorder caused by propionyl‐CoA carboxylase deficiency with frequent neurological involvement, yet cell‐type‐specific mechanisms remain poorly defined. We established human induced pluripotent stem cell (iPSC)‐derived astrocytes (iAs) from patients harboring PCCA or PCCB mutations and investigated ...
Irene González‐Garnacho   +5 more
wiley   +1 more source

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