Results 201 to 210 of about 103,235 (308)

The needle study: Machine learning as a new method for case‐finding in celiac disease

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite a well‐defined diagnostic work‐up, uncertainties persist regarding celiac disease (CeD) detection strategies in the general population. Machine learning (ML) algorithms offer promise in aiding medical decision‐making on clinical data.
Chiara Maria Trovato   +9 more
wiley   +1 more source

Early deglaciation history of the southeastern Baffin Island shelf (Eastern Canadian Arctic Archipelago)

open access: yesJournal of Quaternary Science, EarlyView.
ABSTRACT During the last glacial period, the Laurentide Ice Sheet (LIS) was the largest terrestrial ice sheet on Earth. Its evolution since the Last Glacial Maximum profoundly influenced Earth's geodynamics and surface processes. Investigating the past dynamics of the LIS provides critical insights into how contemporary ice sheets may respond to ...
Alexis P. Belko   +3 more
wiley   +1 more source

Matrine Attenuates Neurological Deficits and Neuroinflammation by Inhibiting the HMGB1/RAGE Axis and Ferroptosis in Intracerebral Hemorrhage Mice

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) is a life‐threatening stroke subtype that lacks effective drug therapy. In the context of ICH, neuroinflammation, and ferroptosis are key contributors to secondary brain injury. In this study, we assessed the neuroprotective effects of matrine (MAT) and its mechanism of action involving the HMGB1/RAGE axis in an ...
Pan‐Di Chen   +7 more
wiley   +1 more source

miR‐9 Restricts Insulin Secretion by Targeting Rab34, Which Mediates Lysosomal Degradation of Proinsulin

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Insulin secretion is a complex, vesicular transport process. Rab34 is a key regulator of intracellular vesicle transport; however, its role in insulin secretion has not yet been reported. miRNA‐9 is vital for the development and progression of the diagnosis and treatment of type 2 diabetes. This study aimed to investigate whether miR‐9 targets
Zhen‐Zhen Guo   +5 more
wiley   +1 more source

Knowledge Gaps, Treatment Preferences, and Unmet Clinical Needs Among Patients With Inflammatory Bowel Disease: A Cross‐Sectional Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study utilized a cross‐sectional survey via a structured questionnaire to evaluate disease‐related knowledge, treatment preferences, and unmet needs among 200 adults with confirmed inflammatory bowel disease (IBD) at a tertiary referral center.
Yi‐Chen Wu   +11 more
wiley   +1 more source

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