Results 121 to 130 of about 37,168 (215)

A noncanonical role for Jagged1 in endothelial mechanotransduction

open access: yesThe FEBS Journal, EarlyView.
This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez   +7 more
wiley   +1 more source

Beyond Compartmentalized L1/L2 Teaching: Connecting Languages to Foster In‐Depth Learning and Multi/Trans Lingual Selves

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT This paper examines elementary Grade 5 and 6 students’ emic perspectives on their L1 French and L2 English teachers’ cross‐curricular efforts to build linguistic and conceptual bridges. Drawing on research on translanguaging pedagogies and recent motivation scholarship, we propose a multi‐competence view of motivation that aligns more closely ...
Sunny Man Chu Lau   +1 more
wiley   +1 more source

Thrombocytopenia in Pregnancy: A 5‐Year Analysis of Characteristics and Practices From a Tertiary Academic Center

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Moderate‐to‐severe thrombocytopenia (platelet count < 100 × 109/L) occurs in fewer than 1% of pregnancies, posing management challenges, particularly surrounding eligibility for neuraxial anesthesia. Although recent anesthesia guidelines recommend a platelet threshold ≥ 70 × 109/L, outcomes data applying these recommendations in ...
Mackenzie E. Lemieux, Ming Y. Lim
wiley   +1 more source

Australian clinical practice guideline: diagnosis and treatment of idiopathic multicentric Castleman disease

open access: yesInternal Medicine Journal, EarlyView.
Abstract Idiopathic multicentric Castleman disease (iMCD) is a rare condition. The pathogenesis is incompletely understood; however, interleukin‐6 (IL‐6) is a major mediator. The clinical presentation is heterogeneous, from mild constitutional symptoms to severe multi‐organ failure.
Dipti Talaulikar   +16 more
wiley   +1 more source

A new sexually dimorphic species of the armoured catfish genus Neoplecostomus (Siluriformes: Loricariidae) from Neotropical Atlantic coastal drainages

open access: yesJournal of Fish Biology, EarlyView.
Abstract A new species of the small‐sized armoured catfish genus Neoplecostomus is described from Neotropical Atlantic coastal drainages, in southeast Brazil. The new species can be readily diagnosed from all congeners by having the first plates of the ventral series reduced in size, rounded and ventrally displaced, resulting in a naked band between ...
Pedro L. C. Uzeda   +5 more
wiley   +1 more source

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