Results 61 to 70 of about 61,193 (294)

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

open access: yesAdvanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang   +12 more
wiley   +1 more source

Modeling a Mixed TCP Vegas and TCP Reno Scenario [PDF]

open access: yes, 2002
In this paper we describe and validate the analytic model of a mixed TCP Reno and TCP Vegas network scenario. There is experimental evidence that TCP Vegas overcomes the widespread TCP version, called TCP Reno, in a number of network environments.
A. DE VENDICTIS, BAIOCCHI, Andrea
openaire   +2 more sources

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

open access: yesAdvanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang   +7 more
wiley   +1 more source

Consideraciones metodológicas para la investigación con simuladores de red

open access: yesInformes Científicos y Técnicos (Universidad Nacional de la Patagonia Austral), 2019
La simulación permite recrear escenarios para su estudio, mediante programas de computadora, sin necesidad de implementarlos en el mundo real. Esto reduce el costo de experimentación e incrementa el nivel de control que se tiene sobre un modelo de ...
Franco Trinidad, Carlos Talay
doaj   +1 more source

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

open access: yesAdvanced Science, EarlyView.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu   +8 more
wiley   +1 more source

Documentos

open access: yesAportes para la Integración Latinoamericana
• MERCADO COMUN DEL SUR (MERCOSUR) 1) LXIV CUMBRE: Comunicado conjunto de los Presidentes de los Estados Partes del MERCOSUR y Bolivia. (8 de julio de 2024) Asunción 2) Declaración presidencial de lucha contra el Crimen Organizado Transnacional (COT).
MERCOSUR ALBA-TCP
doaj   +2 more sources

Test derivation based on tree FSMs and tree automata

open access: yesТруды Института системного программирования РАН, 2018
In this paper, an approach for testing software implementations of telecommunication protocols based on tree finite state machines (FSM) is proposed. The first step is the extraction of the specification Extended FSM from an informal protocol description.
Maria Forostyanova
doaj   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló   +2 more
wiley   +1 more source

Aspects of the ARTCP implementation for the Linux kernel 2.6

open access: yesМоделирование и анализ информационных систем, 2010
The article secifies the ARTCP header format and describes the algorithm of the ARTCP connection establishment. Some aspects of TCP and ARTCP interaction are discussed. Presented a work plan to implement the ARTCP in Linux.
I. V. Alexeev   +2 more
doaj  

Mathematical Prediction for Geometry‐Mediated Cell 3D In‐Growth on Bone Tissue Engineering Scaffolds

open access: yesAdvanced Science, EarlyView.
This study identifies a fundamental pore size dependent pattern of three dimensional bone marrow derived mesenchymal stem cell (BMSC) infiltration within porous scaffolds, where small pores promote horizontal cellular bridging and large pores facilitate vertical migration.
Xiang Gao   +15 more
wiley   +1 more source

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