Results 181 to 190 of about 341,812 (276)

Computational mechanisms of perception in autism revealed using games inspired by rodent operant tasks. [PDF]

Sci Adv
Chakravarty S, Do Q, Li Y, Torres-Lacarra V, Tager-Flusberg H, McGuire JT, Scott BB.   +6 more
europepmc   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li, Yong Wei, Yongshan Li, Yuxiang Dong, Jiancheng Lv, Mingzhi Yuan, Ao Shen, Fuyang Liu, Yetao Zhang, Youjian Li, Ruixi Yu, Yang Liu, Tong Zhao, Jun Wang, Kai Zhou, Zongyao Fan, Manning Wang, Jun Xu, Mulong Du, Min Gu, Bing Yao, Qingyi Zhu   +21 more
wiley   +1 more source

The Neural Cost of Language Processing: Broader Network Recruitment in Adults With Developmental Language Disorder. [PDF]

Neurobiol Lang (Camb)
Abbott NT, Beasley L, Cler GJ.
europepmc   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Mechanochemical Activation of a Bridged‐Exciplex Optical Force Probe

Advanced Science, EarlyView.
A bridged‐exciplex optical force probe is synthesized, switching from solvatochromic charge‐transfer emission in the latent state to intense locally excited emission upon activation. This dual photophysical response with additional changes in quantum yield and fluorescence lifetime enables precise environmental sensing and distinct optical readouts ...
Ronja Schumann, Andreas Bock, Felix Majer, Michael Baumann, Michael Olney‐Fraser, Lev Kazak, Fedor Jelezko, Alexander J. C. Kuehne, Robert Göstl   +8 more
wiley   +1 more source

Bridging Genes and Behavior in Autism Spectrum Disorder: Contributions of OXTR Gene Variants and Methylation to Brain Connectivity Patterns. [PDF]

Psychiatry Investig
Yoon N, Kim S, Oh MR, Kim JI, Lee JM, Kim BN.   +5 more
europepmc   +1 more source

Enhancing Near‐Room‐Temperature Thermoelectric Performance of n‐Type Mg3(Sb, Bi)2‐Based Materials via ZrB2 Heterointerface Engineering

Advanced Science, EarlyView.
A conductive ZrB2 ceramic composite strategy was developed for Mg3(Sb, Bi)2 thermoelectrics to regulate carrier transport and phonon scattering through heterointerface engineering. The 1.0 wt.% ZrB2 composite achieved enhanced room‐temperature performance, with a power factor of 28.51 µW cm−1 K−2 and a peak ZT of 1.22 at 573 K.
Yangyang Xu, Li Zhang, Meng Li, Jie Zhang, Nan‐Hai Li, Yan‐Ling Yang, Xiao‐Lei Shi, Zhi‐Gang Chen   +7 more
wiley   +1 more source

Syntactic priming in children with reading difficulties: evidence from abstract and lexically mediated effects. [PDF]

Front Psychol
Chen X, Dong W, Hu J, Zheng X, Yang J, Jin W, Yang J, Peng P, Wang S.   +8 more
europepmc   +1 more source

Interpretable Deep Learning of Molecule‐Solvent Interactions Using a Solvatochromic Subgroup Contribution Framework

Advanced Science, EarlyView.
Chemistry‐informed deep learning (DL) models based on the solvatochromic subgroup contribution (SSC) framework predict and interpret solvent‐dependent spectral shifts, revealing physically meaningful subgroup‐solvent interactions. ABSTRACT Solvent effects critically influence the photophysical and optical properties of molecules in solution, yet a ...
Jinyong Park, Minhi Han, Kiwoong Lee, Seokwoo Kim, Sungnam Park   +4 more
wiley   +1 more source

Correction: Angiography- and IVUS-tip-detection-guided 3D wiring for CTO and non-CTO percutaneous coronary interventions. [PDF]

Cardiovasc Interv Ther
Okamura A, Yoshikawa R, Tanaka K, Suzuki S, Ishikawa M, Nagai H, Yamasaki T, Yamaji K, Kawamura K, Okamoto N, Ishihara T, Nagamatsu W, Serikawa T, Ito Y, Watanabe H.   +14 more
europepmc   +1 more source