RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis
Advanced Science, EarlyView.Beyond signaling cell death, RIPK3 emerges as a critical metabolic regulator in pulmonary fibrosis. This research reveals that RIPK3 promotes PI3K‐AKT signaling in scar‐associated macrophages to fuel polyamine synthesis, independent of its kinase activity.
Tao Yang +12 more
wiley +1 more source
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
PENGARUH EFIKASI DIRI DAN IKLIM KERJA TERHADAP KINERJA GURU DI SMAN 9 JAKARTA TIMUR [PDF]
, 2015 ARIF TRI WAHYUDI. The Influence of Self Efficacy and Climate Working Against Teacher Performance in SMA 9 East Jakarta. Concentration Education Cooperative Economics, Economics of Education Studies Program, Department of Economics and Administration ...
WAHYUDI, ARIF TRI
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Comparison of creative dietary teaching efficacy and dietary perception according to the frequency of participation of elementary school pre-service teachers in meal preparation [PDF]
Yunhwa Kim, Ji Eun Kim, Kyoungae Lee
openalex +1 more source
Advanced Science, EarlyView.Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian +13 more
wiley +1 more source
THE IMPACT OF TEACHER SELF-EFFICACY ON TEACHING TECHNIQUES: TRADITIONAL OR CONTEMPORARY?
, 2021 Ümit Levent Değirmencioğlu
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Integrating Spatial Proteogenomics in Cancer Research
Advanced Science, EarlyView.Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang +13 more
wiley +1 more source
Professional science knowledge and its impact on confidence in the teaching of earth science : a thesis presented in partial fulfilment of the requirements for the degree of Master of Education at Massey University, Palmerston North, New Zealand [PDF]
, 2002 This study focused on the nature and parameters of the relationships between the professional science knowledge of primary and intermediate teachers and their confidence in teaching in the Making Sense of Planet Earth and Beyond strand of Science in the ...
Haig, Aidan Bruce
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