Results 31 to 40 of about 244,540 (246)

Diagnosis and management of malaria in the intensive care unit

open access: yesJournal of Intensive Medicine
Malaria is responsible for approximately three-quarters of a million deaths in humans globally each year. Most of the morbidity and mortality reported are from Sub-Saharan Africa and Asia, where the disease is endemic.
George Akafity   +2 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Mechanism and reaction kinetics analysis of small-molecule gas formation during thermal decomposition of hydroxylamine nitrate

open access: yesAlexandria Engineering Journal
Hydroxylamine nitrate (HAN) is a new type of high-energy oxidant used in controllable propulsion. The present study explores the reaction mechanism of HAN using density functional theory and constructs reaction mechanism diagrams to understand the ...
Men Li, Tianpeng Li, Xinbao Gao
doaj   +1 more source

LA EVALUACIÓN DE LA DOCENCIA EN LOS PLANES DE MEJORA DE LA UNIVERSIDAD

open access: yesEducación XX1, 2012
En este artículo se consideran la evaluación de la docencia en la Universidad, las fuentes de información y los procedimientos utilizados. Se expone la experiencia realizada en la Universidad de Jaén para iniciar el proceso de evaluación de la ...
Juan Ruiz Carrascosa
doaj   +1 more source

Métrica objetiva y empírica de evaluación de la enseñanza en una Universidad Pública del Sureste de EE. UU.

open access: yesRevista Caribeña de Investigación Educativa, 2020
The marginal contribution of faculty to student learning at an AACSB-accredited College of Business Administration in a public university located in a southeastern state in the United States (U.S.) is measured for the first time by an objective ...
Inessa  Korovyakovskaya   +2 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Urban heat island monitoring and intelligent prediction method based on big data analysis

open access: yesSustainable Energy Research
Frequent extreme heat events in urban areas have brought growing public attention to the urban heat island effect. However, traditional monitoring techniques are unable to handle high-dimensional data, which limits their application in real-world ...
Lin Wang
doaj   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks   +10 more
wiley   +1 more source

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel   +5 more
wiley   +1 more source

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