Results 41 to 50 of about 7,660,667 (264)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Increasing the Effectiveness of Teaching and Learning Process through English Classroom Management

Lingua Didaktika: Jurnal Bahasa dan Pembelajaran Bahasa, 2023
Classroom management is a significant factor in the success of teaching and learning activities. This is a conscious effort to regulate the activities of the teaching and learning process systematically, including preparing teaching materials, providing ...
Novia Robeitah Irham, Farida Repelita Waty Kembaren, Didik Santoso   +2 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Impact of temperature and humidity on the thermal decomposition behavior and the ignition characteristics of Si-based pyrotechnic delay composition

FirePhysChem
This study focuses on analyzing the degradation, ignition, and combustion behavior of a silicon (Si)-based pyrotechnic delay mixture. A comparative analysis is conducted between a fresh sample and one exposed to accelerated aging conditions at a constant
Slimane Bekhouche, Amir Abdelaziz, Ahmed Fouzi Tarchoun, Widad Benchaa, Salim Chelouche, Fateh Chalgoum, Mohammed Jouini, Weiqiang Pang, Djalal Trache   +8 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

GENDER REPRESENTATION IN TEACHING MATERIALS

Armenian Folia Anglistika
The portrayal of gender in teaching materials still mirrors deep-rooted stereotypes even with progress towards equality. The UNESCO Global Education Monitoring Report emphasizes that women and girls remain underrepresented in textbooks and are portrayed
Narine Avanesyan, Anna Knyazyan, Luiza Marabyan   +2 more
doaj   +1 more source

The Effectiveness of Contextual-based Instructional Materials of Elements of Group 15 For Inorganic Chemistry

JPP (Jurnal Pendidikan dan Pembelajaran), 2019
The purpose of research is determine the effectiveness of teaching materials based contextual elements of group 15 for the course of inorganic chemistry. The research design is one group pretest-posttet only. Subjects were students of Chemistry Education
Agtri Wulandari, I Wayan Dasna, Surjani Wonorahardjo   +2 more
doaj   +1 more source

Pengembangan Bahan Ajar Matakuliah Dayung Berbasis Blended Learning untuk Mahasiswa PJKR

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2021
: The purpose of this research and development is to create a teaching material creation based on blended learning (face to face, offline, and online) for rowing teaching materials.
Damaris Marlissa, Wasis Djoko Dwiyogo, Supriyadi Supriyadi   +2 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source