Results 181 to 190 of about 44,929 (317)

Teaching and Learning Urbanism in Architecture Schools

open access: yes, 2018
How are approaches and tools changing to deal with critical territorial challenges, particularly risks associated with climate change, the spatial dimension of the economy and the networked metropolitan region? Are urbanists equipped to lead solutions to our society's challenges to sustainability?
Sánchez Sepúlveda, Mónica   +2 more
openaire   +3 more sources

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

open access: yesAdvanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang   +6 more
wiley   +1 more source

Reflecting Absence; the Nation 9/11 Memorial

open access: yes, 2012
Presented on February 1, 2012 at 6PM in the Reinsch-Pierce Family Auditorium on the GeorgiaTech campus.he Douglas C. Allen annual lecture on landscape architecture was established and endowed by alumni, faculty and friends in honor of Professor Douglas C.
Arad, Michael
core  

Retraction Note: Investigation of the evaluation system of SMEs’ industrial cluster management performance based on wireless network development

open access: yesEURASIP Journal on Wireless Communications and Networking, 2023
Jiang Lan, Wang Chengjun, Zhang Wei
doaj   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine

open access: yesAdvanced Science, EarlyView.
This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng   +18 more
wiley   +1 more source

Design and application of a web-based intelligent ophthalmic image analysis teaching platform. [PDF]

open access: yesFront Med (Lausanne)
Chen J   +7 more
europepmc   +1 more source

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