An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu +10 more
wiley +1 more source
Causal‐Guided Ultra‐Long‐Term Time Series Forecasting Via Anticipated Covariates
Often treated as unknown, information from the future remains underutilized.We demonstrate that in a coupled dynamical system, providing the future state of the effect enables accurate forecasting of the cause for a long timesteps. A time series forecasting paradigm that introduces anticipated covariates to represent such known future states is ...
Jintong Zhao +4 more
wiley +1 more source
Continuous-Variable Quantum Secret Sharing Through Microwave-Enabled Turbulent Channels with Measurement-Device-Independent Scheme. [PDF]
Zhang W, Liang Z, Mao Y, Zhang H, Guo Y.
europepmc +1 more source
A versatile framework integrates addressable electrothermal actuation and strain‐constraint mechanisms to construct programmable shape‐morphing soft matter systems. By combining an analytical inverse design strategy for high‐fidelity 3D surface reconstruction with deep learning‐based closed‐loop control, this approach enables zero‐energy shape locking,
Kai Liu +5 more
wiley +1 more source
The optimization of vocal music teaching by integrating the STEAM concept with the intelligent recommendation system. [PDF]
Su F, Guo Q.
europepmc +1 more source
Based on the largest printable mesoscopic perovskite solar cells database we established, stacking model achieved precise PCE prediction (R2 = 0.73, MAE = 2.18%). Multiple experiments verified the accuracy of the model, which guided the fabrication of high‐PCE devices with an efficiency of 19.36%.
Hao Meng +9 more
wiley +1 more source
A study on the application of multimodal technologies in personalized training systems for the integration of physical education and general education. [PDF]
Lin H, Guo Z.
europepmc +1 more source
REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma
Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu +20 more
wiley +1 more source
Artificial Intelligence-Driven Integrated Risk Assessment of Cardiovascular Disease (AIRA-CVD): A Technical Framework Incorporating Inflammatory Biomarker Signatures and Histopathological Vascular Remodeling. [PDF]
Ogbuefi C.
europepmc +1 more source
Ising machines are emerging as specialized hardware solvers for computationally hard optimization problems. This review examines five major platforms—digital CMOS, analog CMOS, emerging devices, coherent optics, and quantum systems—highlighting physics‐rooted advantages and shared bottlenecks in scalability and connectivity.
Hyunjun Lee, Joon Pyo Kim, Sanghyeon Kim
wiley +1 more source

