Results 71 to 80 of about 1,537,856 (291)

A QUBO Framework for Team Formation

The team formation problem assumes a set of experts and a task, where each expert has a set of skills and the task requires some skills. The objective is to find a set of experts that maximizes coverage of the required skills while simultaneously minimizing the costs associated with the experts.
Karan Vombatkere, Evimaria Terzi, Theodoros Lappas   +2 more
openaire   +2 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

COMPARISON OF TOOLS AND METHODS OF FORMING AN IT PROJECT TEAM IN THE CONTEXT OF CASCADING AND FLEXIBLE PROJECT DEVELOPMENT

Sustainable Development and Engineering Economics
In the context of digital transformation, the formation of well-balanced project teams has become one of the critical factors for the successful implementation of IT projects.
Maxim Dergachev, Salbek Beketov, Alexey Gintciak   +2 more
doaj   +1 more source

Team Formation in Software Engineering: A Systematic Mapping Study

IEEE Access, 2020
Context: Software team formation is an important project management activity. However, forming appropriate teams is a challenge for most of the companies.
Alexandre Costa, Felipe Ramos, Mirko Perkusich, Emanuel Dantas, Ednaldo Dilorenzo, Ferdinandy Chagas, Andre Meireles, Danyllo Albuquerque, Luiz Silva, Hyggo Almeida, Angelo Perkusich   +10 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Influences on the Formation of Coach-Athlete Relationships [PDF]

, 2018
For a team to be successful, coaches and players need to have a good relationship. Without this relationship there can be tension within the team that hinders success.
Rinaldo, Anthony
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Using machine learning to predict links and improve Steiner tree solutions to team formation problems - a cross company study

Applied Network Science, 2020
The team formation problem has existed for many years in various guises. One important challenge in the team formation problem is to produce small teams that have a required set of skills.
Peter Keane, Faisal Ghaffar, David Malone   +2 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source