Results 161 to 170 of about 232,228 (275)

The Evolutionary Trajectory and Prognostic Value of GITR+ Tregs Reprogramed by Tumor‐Intrinsic PD‐1/c‐MET Signaling in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), tumor‐intrinsic PD‐1 signaling activates the MET pathway, leading to the establishment of an immunosuppressive tumor microenvironment (TME). This MET‐driven signaling cascade promotes the selective accumulation of GITR+ regulatory T cells (Tregs), a highly immunosuppressive subset.
Jiande Han, Hanlin Yin, Taochen He, Junyi He, Zhenlai Jiang, Qiangda Chen, Zhihang Xu, Yuqi Xie, Yaolin Xu, Haibo Wang, Wenquan Wang, Wenchuan Wu, Yun Jin, Wenhui Lou, Jun Yu, Ning Pu, Liang Liu   +16 more
wiley   +1 more source

Exploring medical humanities from heterogeneous focus groups: A thematic analysis. [PDF]

Tzu Chi Med J
Yi LY, Tseng TC, Chu SY.
europepmc   +1 more source

Pushing the Frontiers: Artificial Intelligence (AI)‐Guided Programmable Concepts in Binary Self‐Assembly of Colloidal Nanoparticles

Advanced Science, EarlyView.
Colloidal nanoparticles self‐assembly advances towards intelligent, customized assembly through precise control of binary co‐assemblies. This review explores the evolution from monolithic to binary assemblies, highlighting how the AI‐guided programmable assembly approach has the potential to shift from passive assembly to active intelligent design.
Cancan Li, Lindong Ma, Zhenjie Xue, Xiao Li, Shan Zhu, Tie Wang   +5 more
wiley   +1 more source

Qualitative Research Leaders: Evaluation of Pilot Global Pipeline Program. [PDF]

Am J Trop Med Hyg
Hennink MM, Ingles DJ, Mmbaga BT, Prabhakaran D, Heimburger DC, Johnson LCM.   +5 more
europepmc   +1 more source

Exploring the Digital Divide among the Bhutanese Refugee Community during COVID-19: Engaged Research in Action. [PDF]

Int J Environ Res Public Health, 2022
Cohen JH, Maleku A, Pyakurel S, Suzuki T, Raut S, Montiel Ishino FA.   +5 more
europepmc   +1 more source

Breaking the Cycle: Integrating the Mathematics Specialist [PDF]

, 2007
Hulen, T.
core   +1 more source

Microsphere Strategy to Generate Conformal Bone Organoid Units with Osteoimmunomodulation and Sustainable Oxygen Supply for Bone Regeneration

Advanced Science, EarlyView.
Oxygen‐releasing immunomodulatory microspheres are used to construct conformal bone organoid units that enhance osteogenesis, angiogenesis, and immune regulation. By integrating BMSCs, macrophages, and CaO₂‐HAp into a SilMA‐based hydrogel platform, this strategy provides sustained oxygen supply and anti‐inflammatory microenvironments, leading to ...
Anfu Deng, Hao Zhang, Yan Hu, Jilong Li, Jian Wang, Xiao Chen, Zhen Geng, Ke Xu, Yuxiao Lai, Jianhua Wang, Yingying Jing, Long Bai, Jiacan Su   +12 more
wiley   +1 more source

Large language models can consistently generate high-quality content for election disinformation operations. [PDF]

PLoS One
Williams AR, Burke-Moore L, Chan RS, Enock FE, Nanni F, Sippy T, Chung YL, Gabasova E, Hackenburg K, Bright J.   +9 more
europepmc   +1 more source

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

Advanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang, Leilei Yang, Jing jiao, Wenshuai Li, Sen Lin, Xianlong Zong, Haoyang Qin, Danfeng Liu, Rui Li   +8 more
wiley   +1 more source

Moving graduate and professional education forward to develop leaders equipped to effectively address wicked problems. [PDF]

New Dir Stud Leadersh, 2022
Kaufman EK, Stedman NL.
europepmc   +1 more source