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Tear Film Stability and Tear Break Up Time (TBUT) in Laboratory Rabbits—A Systematic Review
Several older studies on rabbits indicated that the pre-corneal tear film was unusually stable and this perspective was revisited recently. However, the methods used for these studies were very different from those generally used in human studies. A literature search was undertaken for the time period of 1965 through 2017, mainly using PubMed, to ...
Michael J Doughty
exaly +5 more sources
Aim: To compare the outcomes of non-invasive break-up time (NI-BUT) test and the other conventional dry eye tests.Methods: The right eyes of 170 subjects were included in the study. In order to evaluate the tear quality of the patients, NI-BUT levels were measured by the Scheimplug-Placido disk system (Sirius topography).
Kemal Özülken +2 more
exaly +4 more sources
Tear film break‐up time in rabbits [PDF]
Rabbits have a longer inter-blink time (approximately 10 minutes) compared with humans (five to eight seconds), suggesting that rabbits have a much more stable tear film. Using fluorescein, the tear break-up time of rabbits has been reported to be similar to that of humans.
Maria Markoulli +2 more
exaly +3 more sources
Non‐invasive tear break‐up time in normal Malays [PDF]
Tear stability in normal Malays with consideration of gender and age has not been reported. In this study, we measured tear stability in normal Malays using the non-invasive tear break-up time (NIBUT).Forty-eight Malay subjects aged seven to 60 years were recruited from among the staff, their children and students of the faculty.
Maurice Yap, Norhani Mohidin
exaly +3 more sources
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Tear break-up time is related to blink frequency
Acta Ophthalmologica, 1991Abstract The relationship between tear break‐up time and blink frequency was investigated in a group of 41 subjects. A significant relationship between tear breakup time and blinking was found. This suggests that tear stability plays an important role in stimulating normal involuntary blinking.
Maurice Yap
exaly +3 more sources
Ability of non-invasive tear break-up time to determine tear instability in contact lens wearers [PDF]
Abstract Purpose To evaluate the performance of precorneal and prelens non-invasive tear break-up time (NIBUT) measurements to determine tear instability in contact lens (CL) wearers.Methods In this study 50 eyes of CL wearers were evaluated.
Ersin Muhafiz
exaly +4 more sources
Study of tear film flow and break up time (BUT) in trachoma
Acta Ophthalmologica, 1986Abstract Tear film flow and stability studies were carried out in patients suffering from cicatrizing trachoma by Schirmer test I and tear film break‐up‐time (BUT) measurements, respectively. Both Schirmer test I and BUT values were decreased significantly (t‐test, P < 0.001) depicting aqueous as well as mucin deficiency and hence, an unstable tear ...
A K Khurana
exaly +3 more sources
Inter-week variation of meibometry and tear break-up time in healthy subjects
Variation with time in the tear film parameters should be considered by the clinician since the time when measurements are made can influence proper diagnosis.A hallmark of dry eye is an unstable tear film associated with variability in objective daily measures. The purpose of the present study was to evaluate the inter-week repeatability of meibometry,
Hugo Pena-Verdeal +2 more
exaly +4 more sources
Age, Gender, and Tear Break-Up Time
Optometry and Vision Science, 1993ABSTRACT We investigated the effect of age and gender on the tear break‐up time (TBUT) of 2 groups of normal, asymptomatic subjects [92 Hong Kong‐Chinese (HK‐Chinese) and 76 Singapore‐Chinese (S‐Chinese)] using the conventional fluorescein‐instillation technique.
P, Cho, M, Yap
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Review of the Tear Break-Up Time and a Closer Look at the Tear Break-Up Time of Hong Kong Chinese
Optometry and Vision Science, 1993ABSTRACT The technique of assessing tear stability using the fluorescein instillation technique has been widely used in the clinical diagnosis of “dry eye” and in the screening of potential contact lens wearers. Various inconsistencies in the application of the tear break‐up time (TBUT) techniques and the results obtained were noted ...
P, Cho, B, Brown
openaire +2 more sources

