Results 131 to 140 of about 22,884,951 (242)

Therapeutic effects of 3% diquafosol ophthalmic solution in patients with short tear film break-up time-type dry eye disease. [PDF]

BMC Ophthalmol, 2018
Mun Y, Kwon JW, Oh JY.
europepmc   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Sulfur–Oxygen Competitive Coordination Allosteric Hydrogel for Triboelectric Nanogenerator‐Based Intelligent Tactile Recognition

Advanced Science, EarlyView.
A dynamic Ag+─S coordinated hydrogel with a sulfur–oxygen competitive coordination allosteric switch enables reversible tuning between soft–adhesive and stiff–robust states. Integrated with a lightweight 1DCNN classifier, the smart glove system achieves 99.70% laboratory and 93.35% real‐wear material recognition accuracy, offering a paradigm for self ...
Shixia Lan, Lin Zhang, Yunyun Dong, Yongyun Mao, Wanbiao Hu   +4 more
wiley   +1 more source

A Scalable Double‐Sided Wet Etching Strategy for Large‐Area Mushroom‐Shaped Bionic Adhesives

Advanced Science, EarlyView.
This work presents a scalable manufacturing strategy for high‐performance, large‐area, mushroom‐shaped bio‐inspired adhesives. Using a double‐sided wet etching process, the complex 3D metal molds are fabricated rapidly and controllably. The resulting adhesive structures exhibit strong, stable adhesion under various conditions, including atmosphere and ...
Keju Ji, Xinran Xu, Jian Chen, Wenjie Chen, Xiaolei Zhu, Haixiang Ma, Xingyu Jiang, Changhong Linghu, Zhendong Dai   +8 more
wiley   +1 more source

Tear film stability assessment by corneal reflex image degradation

A method for tear film break up measurements based on the degradation of corneal reflex images caused by dry spots is presented. The experimental setup, which is based on recording the corneal reflex image or the first Purkinje image, is described, as ...
García Guerra, Carlos Enrique, Aldaba Arévalo, Mikel, Pujol Ramo, Jaume, Mira Agudelo, Alejandro, Barrera, John Fredy   +4 more
core  

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

Advanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho, Jinsook Ahn, Jimin Yang, Dong Sun Lee, Gahi Hong, Sangkyu Lee, Ho Min Kim   +6 more
wiley   +1 more source

The Distribution and Influence Factors of Non-Invasive Tear Film Break-Up Time in Children [Letter]. [PDF]

Clin Ophthalmol
Rani A, Yadav RK.
europepmc   +1 more source

A Recyclable and Biodegradable High‐Performance Piezoelectric Nanogenerator for Self‐Powered Biosensing and Assistive Human‐Machine Interaction

Advanced Science, EarlyView.
By exploiting multiscale hydrogen‐bonding interactions between HFPD and TOCNF, the composite simultaneously achieves a high piezoelectric coefficient (14.0 pC·N−1), outstanding flexibility (100 000 bending cycles), water‐assisted recyclability, excellent biodegradability, and sensitive wearable/implantable sensing for motion, speech, and Morse code ...
Tingshuai Luo, Tian Xiao, Luyu Zhang, Bailang Zhang, Shengchang Lu, He Xiao, Jianguo Li, Kai Liu, Chaoji Chen, Hui Wu   +9 more
wiley   +1 more source

Strengthening Constitutive Motifs in Isotropic Fibrous Hydrogel for Exceptional Damage Resistance

Advanced Science, EarlyView.
An orientation‐free strategy is reported for fabricating damage‐resistant hydrogels by strengthening constitutive motifs in isotropic fibrous (IF) networks. Through nonsolvent quenching followed by salting‐out, IF networks are generated and their multiscale constituents are subsequently reinforced, yielding dense and crystalline isotropic nanofiber ...
Bolin Wan, Xule Yang, Liju Xu, Dong Qiu
wiley   +1 more source