Results 51 to 60 of about 79,292 (170)

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

Advanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen, Jiahui Lai, Qiongjiao Zeng, Liangbin Zhou, Boguang Yang, Bin Zhang, Min Wang, Jiajing Zhou, Kieran Lau, Khoon S. Lim, Zhong Alan Li, Rocky S. Tuan   +11 more
wiley   +1 more source

Changes in Tear Osmolarity after Cataract Surgery

Journal of Nippon Medical School, 2021
The purpose of this study was to examine changes in the ocular surface before and after phacoemulsification with small incisions and to examine the changes in tear osmolarity.This was a prospective, observational study involving 55 eyes of 39 patients (19 male, 20 female patients; average age 72.0±7.3 years) who had cataract surgery at a Nippon Medical
Igarashi, Tsutomu, Takahashi, Hisatomo, Kobayashi, Maika, Kunishige, Tomoyuki, Arima, Takeshi, Fujimoto, Chiaki, Suzuki, Hisaharu, Okuda, Takahisa, Takahashi, Hiroshi   +8 more
openaire   +3 more sources

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

Advanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin, Jiani Li, Panqin Ma, Shinan Wu, Wenying Guan, Yimin Huang, Ke Feng, Mingyan Wei, Zixuan Yang, Shujia Guo, Caihong Huang, Yun‐Long Wu, Yi Han, Zuguo Liu   +13 more
wiley   +1 more source

Dual‐Dynamically Crosslinked Nanogels Enable Prolonged Ocular Retention for Multimodal Dry Eye Therapy

Advanced Science, EarlyView.
This berberine‐loaded dual‐dynamically crosslinked nanogel integrates tannic acid‐zinc metal‐phenolic networks and carboxymethyl chitosan/aldehyde‐functionalized poly(ethylene glycol) dynamic Schiff base networks, achieving 1‐year colloidal and antioxidant stability, sustained corneal berberine exposure for 24 h to support convenient once‐daily dosing,
Yanru Xin, Sisi Chen, Shengli Huang, Mengqi Huang, Jingyan Zhu, Zijian Wang, Jianliang Shen, Qinxiang Zheng   +7 more
wiley   +1 more source

Correlation of Non-Invasive Tear Break-Up Time With Tear Osmolarity and Other Invasive Tear Function Tests

, 2020
Aim: To compare the outcomes of non-invasive break-up time (NI-BUT) test and the other conventional dry eye tests. Methods: The right eyes of 170 subjects were included in the study.
Aydemir, Gozde Aksoy, Mumcuoğlu, Tarkan, Aksoy Aydemir, Gözde, Özülken, Kemal, Tekin, Kemal   +4 more
core   +1 more source

Relationships among Tear Film Stability, Osmolarity, and Dryness Symptoms [PDF]

, 2015
PurposeTo examine the relationships among tear osmolarity, tear film stability, and several measures of dry eye (DE) symptoms in a multivariable analysis.MethodsA cross-sectional study was conducted with 137 subjects (68 non-contact lens [CL] wearers and
Yeh, Thao N, Lin, Meng C, Graham, Andrew D   +2 more
core   +1 more source

Tear Osmolarity as a Biomarker for Dry Eye Disease Severity

, 2010
PURPOSE. To study the association between tear osmolarity and dry eye severity grade, based on a modified Dry Eye Workshop (DEWS) scale, and between osmolarity and the signs and symptoms that determine dry eye disease severity. METHODS. Nineteen patients
Massingale, Morgan L., Asbell, Penny A., Suzuki, Mari, Godbold, James, Ye, Fen, Vallabhajosyula, Maithreyi, Elfassy, Tali, Morgan L. Massingale, James Godbold, Fen Ye, Tali Elfassy, Penny A. Asbell, Mari Suzuki, Maithreyi Vallabhajosyula   +13 more
core   +1 more source

Changes in tear film osmolarity after 25G+ PPV

BMC Ophthalmology, 2020
Background The aim of our study was to assess changes of tear film osmolarity after micro-incision 25G+ pars plana vitrectomy (PPV) in a prospective study.
J. Němčanský, A. Kopecký, P. Mašek
doaj   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

The tear substitutive therapy for prophylaxis and treatment of dry eye after cataract surgery

Oftalʹmologiâ, 2014
Purpose: To study the efficiency of tear substitutes based on hyaluronic acid at the patients after phacoemulsification for prophylaxis and postoperative therapy of dry eye syndrome.Methods: 168 patients (168 eyes) were examined before cataract surgery ...
V. N. Trubilin, T. A. Sedneva, S. G. Kapkova   +2 more
doaj   +3 more sources