Results 41 to 50 of about 267,888 (277)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Mullins effect under tearing mode and its reversibility of ethylene-vinyl acetate copolymer/chloroprene rubber thermoplastic vulcanizates

open access: yesHecheng xiangjiao gongye, 2023
Thermoplastic vulcanizate (TPV) based on ethylene-vinyl acetate copolymer (EVA)/chloroprene rubber (CR) blends were prepared by dynamic vulcanization. Its micromorphology, tearing strength, Mullins effect and reversible behavior and its mechanism under ...
LU Xun1, WANG Jun-hao2, ZHU Da-zhi1, WANG Zhao-bo1
doaj   +1 more source

3-d resistive MHD simulations of magnetic reconnection and the tearing mode instability in current sheets

open access: yes, 2008
Magnetic reconnection plays a critical role in many astrophysical processes where high energy emission is observed, e.g. particle acceleration, relativistic accretion powered outflows, pulsar winds and probably in dissipation of Poynting flux in GRBs ...
G. C. MURPHY   +3 more
core   +3 more sources

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Hot tearing susceptibility of aluminum alloys using CRCM-Horizontal mold

open access: yesResults in Physics, 2017
Hot tearing is one of the common defects in casting products. Hot tearing susceptibility (HTS) is evaluated using three casting temperatures: 710, 760 and 810 °C.
H. Akhyar   +3 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Influence and evaluation of constraint on fracture toughness in pipeline research [PDF]

open access: yes, 2012
Accessing nowadays fossil fuel reserves requires a strain-based design approach. Within such design, the ductile tearing resistance is a key parameter in assessing the defect tolerance. To determine this tearing resistance, full scale (pressurized) tests
De Waele, Wim   +3 more
core  

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Influence of alloying elements on hot tearing susceptibility of Mg–Zn alloys based on thermodynamic calculation and experimental

open access: yesJournal of Magnesium and Alloys, 2018
Based on the hot tearing index |∆T/∆(fs)0.5| recently proposed by Kou and the thermodynamic calculations of Pandat software, Al, Cu, and Mn elements were picked up and their influence on hot tearing susceptibility of Mg–xZn (x = 6, 8, 10, wt%) alloys was
Zhenzhen Yang   +6 more
doaj   +1 more source

Sound-Based Improved DenseNet Conveyor Belt Longitudinal Tear Detection

open access: yesIEEE Access, 2022
At present, conveyor belt tearing is the most serious fault of belt conveyor, causing the greatest loss. This paper aims to overcome the issues of poor accuracy, low precision, and poor real-time performance in the longitudinal tear detection of the ...
Di Miao, Yimin Wang, Shixin Li
doaj   +1 more source

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