Results 241 to 250 of about 771,186 (352)

Comparison of articular-sided, bursal-sided, and intratendinous partial rotator cuff tears: outcomes of surgical repair from a multicenter cohort study. [PDF]

J Orthop Surg Res
Audigé L, Baum C, Stojanov T, Rosso C, Moroder P, Suter T, Dao Trong ML, Benninger E, Moor B, Spormann C, Durchholz H, Cunningham G, Lädermann A, Schär M, Flury M, Eid K, Scheibel M, Candrian C, Jost B, Zumstein MA, Wieser K, ARCR_Pred Study Group, M Müller A.   +22 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Concomitant Lateral Meniscal Tears in Pediatric and Adolescent Patients Undergoing Combined Medial Meniscal Ramp Lesion Repair and Anterior Cruciate Ligament Reconstruction Are Frequently Missed on MRI, Are Often Vertical or Root Tears, and Are Usually Repaired: A Multicenter Study. [PDF]

Orthop J Sports Med
Moran J, Amaral JZ, Tollefson LV, Jones RH, Dave U, Lee MS, LaPrade CM, Katz LD, Porrino J, Salandra JM, Allen CR, Gardner E, Jimenez AE, Medvecky MJ, Hewett TE, Verma NN, Chahla J, Fabricant PD, McKay SD, LaPrade RF.   +19 more
europepmc   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Dural tears from traumatic spinal fractures: an illustrative case and systematic review of its incidence, diagnosis, risk factors, and management. [PDF]

J Spine Surg
Chan KCA, Yick HTV, Kwan KYH.
europepmc   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Incidence and geographic mapping of meniscal tears in acute ACL injuries with meticulous posterior arthroscopic evaluation: longitudinal tears at the posterior menisco-capsular junction are the most common tear pattern in acute ACL injuries. [PDF]

Knee Surg Relat Res
Kim DH, Lee DK.
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Does the timing of ACL reconstruction affects meniscal tear type?: A retrospective cohort study. [PDF]

Medicine (Baltimore)
Sabir MA, Özbek RB, Aydemir S.
europepmc   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source