Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes
Advanced Science, EarlyView.Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang +14 more
wiley +1 more source
Differential association of primary and alternative σ factors with RNA polymerase of Mycobacterium tuberculosis during transcription elongation. [PDF]
Nucleic Acids ResHazra N, Mukhopadhyay J.
europepmc +1 more source
Dilution Effect for High‐Performance Multiple‐Component Near‐Infrared Organic Photodetectors
Advanced Science, EarlyView.The dilution effect in multi‐component organic photodetector effectively suppresses non‐radiative decay and minimizes dark current, while energy‐level‐offset‐governed electron transfer between acceptors maintains efficient charge transport. This synergistic mechanism collectively enables remarkable device performance, including high detectivity and ...
Zhuang Li +9 more
wiley +1 more source
A single-center retrospective study of prophylactic loop ileostomies and transverse end colostomies after laparoscopic radical resection for rectal cancer: a comparison of safety and functional outcomes. [PDF]
Int J Colorectal DisLi Y +11 more
europepmc +1 more source
Photon‐to‐Heat Energy Harvesting Fluorescent Protein Coatings for Thermoelectrics
Advanced Science, EarlyView.Fluorescent proteins (FPs) are used in light‐absorbing coatings on thermoelectric generators (TEGs) to convert light into heat and generate electricity. By tuning the properties of FP‐doped polymer matrices, photothermal efficiencies of up to 48% have been achieved.
Anna Zieleniewska +3 more
wiley +1 more source
ROS-scavenging nanoparticles loaded with tectorigenin protect against acetaminophen-induced hepatotoxicity by interrupting the calcium/ROS-mediated pathogenic endoplasmic reticulum-Mitochondrial signaling cascade. [PDF]
Bioact MaterZhang Y +6 more
europepmc +1 more source
Spectroscopic Evidence of Edge‐Localized States in an Antiferromagnet Topological Insulator NdBi
Advanced Science, EarlyView.Using spin‐polarized scanning tunneling microscopy (STM) in conjunction with quasiparticle interference, we successfully identify distinct signatures of the ferromagnetic and antiferromagnetic terminations in NdBi, a rare‐earth monopnictide exhibiting non‐trivial topology and magnetism. We demonstrate that step edges on ferromagnetic surfaces host well‐
Avior Almoalem +8 more
wiley +1 more source