Results 11 to 20 of about 88,639 (304)
Phylogeny of Tec Family Kinases: Identification of a Pre-Metazoan Origin of Btk, Bmx, Itk, Tec, Txk and the Btk Regulator SH3BP5 [PDF]
It is generally considered mammals and birds have five Tec family kinases (TFKs): Btk, Bmx (also known as Etk), Itk, Tec, and Txk (also known as Rlk). Here, we discuss the domains and their functions and regulation in TFKs.
Ortutay, Csaba +11 more
core +2 more sources
NS1-Induced PARP1 Phase Transitions Prolongs Host Transcriptional Pausing to Promote Influenza A Virus Replication. [PDF]
After IAV infection, NS1 induces PARP1 phase transition, reducing molecular mobility in condensates, prolonging host transcriptional pause, aiding RdRp cap snatching, and promoting viral transcription. ABSTRACT Influenza A virus (IAV) commandeers host transcriptional machinery to replicate, but mechanisms remain elusive.
Ma S +12 more
europepmc +2 more sources
基于2018年8月5日印度尼西亚地震震中(116.45°E,8.33°S)附近的澳大利亚达尔文站和位于震中磁力线共轭区域的武汉站的电离层测高仪观测数据,以及相同区域全球卫星导航系统接收机的观测数据,对该地震震前的电离层异常扰动特征进行了分析。结果显示,震前同时观测到了电离层F2层临界频率(foF2)和总电子含量(TEC)时间序列的异常。基于岩石圈-大气层-电离层直流电场耦合模式和美国国家大气研究中心的热层-电离层环流耦合模式(NCAR/HAO TIEGCM ...
Zhuangkai Wang +4 more
doaj +1 more source
Distributed arrays of ground-based instruments can help advance observations and improve understanding of space weather. The implementation of an array of sensors can be constrained, however, by the high cost of commercial instruments and the ...
Wright Isaac G. +4 more
doaj +1 more source
Printing-Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling. [PDF]
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Moore SR +6 more
europepmc +2 more sources
Bessel’s method in study of solar eclipse influence on the ionosphere
Relevance. A solar eclipse is a global disturbing factor that significantly changes the characteristics of the ionosphere. As is known, the ionosphere affects the propagation of radio waves of all ranges, that is, it affects the operation of navigation ...
Yu. B. Mylovanov, V. L. Dorokhov
doaj +1 more source
Improving word embeddings in Portuguese: increasing accuracy while reducing the size of the corpus [PDF]
The subjectiveness of multimedia content description has a strong negative impact on tag-based information retrieval. In our work, we propose enhancing available descriptions by adding semantically related tags. To cope with this objective, we use a word
José Pedro Pinto +3 more
doaj +2 more sources
Los grandes volúmenes de residuos textiles y contaminación producidos por la industria de la moda y en especial por el fast fashion, la necesidad cada vez más inminente de exclusividad y privilegio de los consumidores, y el avance exponencial de la implementación de tecnología en productos cotidianos nos llevan a plantear Dress Tec, a un clic de tu ...
Romero Sierra, María Camila +3 more
openaire +1 more source
Evaluation of Hands-Free VR Interaction Methods During a Fitts’ Task: Efficiency and Effectiveness
Currently, it is standard to use tracked handheld controllers for interaction in immersive virtual reality (VR). However, since VR interactions are becoming more natural with hand tracking, it is important to provide hands-free alternatives for selection
Pedro Monteiro +4 more
doaj +1 more source

