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Making Technetium-99m

Chemical & Engineering News Archive, 2012
The key medical isotope technetium-99m can be produced directly in hospital cyclotrons, rather than by extracting the isotope from material made in nuclear reactors, a team of Canadian researchers ...
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Discordant Uptake of Technetium-99m DISIDA and Technetium-99m Sulfur Colloid in an Amebic Abscess

Clinical Nuclear Medicine, 1988
Hepatobiliary imaging in a patient with an amebic abscess showed an early cold defect that later showed rim enhancement. A Tc-99m SC scan did not show prominent flow (making hepatoma unlikely) and showed the previously noted defect to appear larger and without rim enhancement.
John Foster   +2 more
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Technetium-99m mercaptoalbumin as a potential substitute for technetium-99m labelled red blood cells

European Journal of Nuclear Medicine, 1993
Technetium-99m labelled red blood cells (99mTc-RBCs) are far superior to 99mTc-labelled human serum albumin (99mTc-HSA) for radionuclide ventriculography, but their labelling is more complex, time consuming and risk bearing (in vitro labelling) or suffers from interference by some medications (in vivo labelling).
Alfons Verbruggen   +3 more
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Comparison of technetium 99m-phytate and technetium 99m-sulphur colloid in primary bone tumours

European Journal of Nuclear Medicine, 1990
Eleven patients with proven primary bone tumour (five Ewing sarcomas, six osteosarcomas) and two cases of metastatic bone involvement (primary other than bone) were investigated with 99mTc-phytate and 99mTc-sulphur colloid to compare the behaviour of the two radiopharmaceuticals at the tumour site.
M K Bhargava   +5 more
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Technetium-99m radiopharmaceuticals

1995
Technetium is a group VIIB transition element which has seven electrons beyond the noble gas electronic configuration. The other members of the group are manganese (Mn) and rhenium (Re); together they form a triad (Mn, Tc, Re). All three elements easily lose the seven electrons to yield the +7 oxidation state of permetallate anions (MnO− 4, TcO− 4, ReO−
Samy Sadek   +2 more
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Reproducibility of technetium-99m ethylenedicysteine clearance

European Journal of Nuclear Medicine and Molecular Imaging, 1999
It has been shown that technetium-99m ethylenedicysteine ((99m)Tc-EC) clearance displays a strong correlation with orthoiodohippurate clearance and that it is possible to estimate effective renal plasma flow from (99m)Tc-EC clearance. However, in routine practice, when monitoring renal function of patients by clearance determinations it is imperative ...
Metin Halac   +4 more
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Uptake of technetium 99m MDP by hepatoblastoma

European Journal of Nuclear Medicine, 1987
Focal uptake of 99mTc-MDP was seen in a case of hepatoblastoma. The focal uptake corresponded to an area of calcification on CT, which was shown histologically to consist of osteoid with mineralization. The mechanism of uptake by the tumor in this case is likely to be the same as for skeletal uptake.
David A. Cory   +2 more
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Technetium-99m Radiopharmaceuticals

2010
The name technetium was derived by the scientist Mendeleyev from the Greek word technetos, meaning “artificial.” Technetium-99m was discovered in 1937 by Perrier and Segre in a sample of naturally occurring 98Mo irradiated by neutrons and deuterons. The first generator as a source for Tc-99m was introduced in 1957 at the Brookhaven National laboratory,
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Cationic complex of technetium-99m.

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology, 1989
The invention relates to a cationic complex of technetium-99m with (a) at least one bidendate ligand X having the formula R1 R2 ZQZR3 R4 where each Z is phosphorus or arsenic, Q is a (CH2)n linking group where n is 2 to 8 or a 1,2-phenylene linking group, each of R1, R2, R3 and R4 is hydrogen, C1 to C5 alkyl or phenyl; and (b) at least one monodentate ...
Frank Brady   +3 more
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Organ Visualisation with Technetium 99m Preparations

The British Journal of Radiology, 1967
Abstract Selected examples are presented in this paper to illustrate the potentialities of the use of some of the 99mTc compounds for organ visualisation. Although no attempt has been made at clinical evaluation, the additional information which can be gained by this means is both useful and impressive to those familiar with the technique.
P. Schenck, I. Kazem, P. Gelinsky
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