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Excretion of technetium 99m hexakismethoxyisobutylisonitrile in milk

European Journal of Nuclear Medicine, 1991
The amount of radioactivity excreted in breast milk following the administration of technetium 99m hexakismethoxyisobutylisonitrile (99mTc-MIBI) to a patient referred for cold spot myocardial scintigraphy was determined. During the first 24 h after administration, only 41.2 kBq 99mTc (0.0084% of the injected dose) was excreted in 448 ml milk with the ...
Rubow S.M.   +3 more
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Technetium-99m-labeled liposomes to image experimental colitis in rabbits: comparison with technetium-99m-HMPAO-granulocytes and technetium-99m-HYNIC-IgG.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998
Scintigraphic techniques are routinely used for the evaluation of the extent and severity of inflammatory bowel disease. Currently, the radiopharmaceutical of choice is 99mTc-hexamethyl propyleneamine oxime (HMPAO)-leukocytes. We studied the imaging potential of two recently developed 99mTc-labeled agents, polyethylene glycol (PEG)-coated liposomes and
Dams, E.T.M.   +7 more
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Use of Technetium–99m in Hepatic Scintillography

Nature, 1965
HARPER et al.1 have recently pointed out the excellent possibilities of technetium–99m in medical scintillography.
Degrossi O   +4 more
openaire   +3 more sources

The Radiopharmaceutical Chemistry of Technetium-99m

2019
Technetium-99m (99mTc) is a radiometal that has nearly ideal nuclear properties for diagnostic nuclear medicine imaging, which has helped make it high impact and extensively utilized radionuclide in medicine. 99mTc-based imaging—which can be done using a simple gamma camera or a more advanced 3-D method known as single photon emission computed ...
Denis P. Snider   +5 more
openaire   +2 more sources

Technetium-99m chelates as radiopharmaceuticals

1996
Technetium-99m (99mTc) is currently, and will be in the foreseeable future, the most widely used radionuclide used in virtually all clinical diagnostic Nuclear Medicine laboratories in the world. Several 99mTc radiopharmaceuticals that are routinely used have become important factors in decisions on the diagnosis and treatment of patients with a ...
Silvia S. Jurisson, Wynn A. Volkert
openaire   +2 more sources

Technetium-99m-MIBI Uptake in Bone Metastases

Journal of Women's Imaging, 2005
Aim: The purpose of this study was to determine the potential of Tc-99m hexakis-2-methoxyisobutylisonitrile (MIBI) for detection of bone metastases in breast cancer patients in comparison to Tc-99m methylene diphosphonate (MDP) bone scans. Materials and Methods: Tc-99m MIBI and Tc-99m MDP scans were performed in 55 patients with breast cancer and ...
Buyukdereli G.   +3 more
openaire   +3 more sources

Comparison of technetium-99m-MDP, technetium-99m-WBC and technetium-99m-HIG in musculoskeletal inflammation.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998
This study compared three radionuclide techniques in distinguishing musculoskeletal infection from noninfectious inflammation.Thirty-five orthopedic patients with suspected musculoskeletal infection were examined using three radionuclide techniques in sequence: triphasic bone scintigraphy, 99mTc radioleukocytes (99mTc-WBC) scintigraphy and 99mTc human ...
F, Palermo   +6 more
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Technetium‐99m radiochemistry for pharmaceutical applications

Journal of Labelled Compounds and Radiopharmaceuticals, 2017
Technetium‐99m (99mTc) is a widely used radionuclide, and the development of 99mTc imaging agents continues to be in demand. This overview discusses basic principles of 99mTc radiopharmaceutical preparation and design and focuses on the 99mTc radiochemistry relevant to its pharmaceutical applications. The 99mTc complexes are described based on the most
openaire   +2 more sources

Bifunctional Chelators for Technetium-99m

1996
Technetium-99m has nearly optimal characteristics as a radionuclide for diagnostic radiopharmaceuticals: (1) a low radiation dose to the patients due to the absence of a-and β-radiation and the short physical half-life (6.02 h), (2) the excellent quality of its scintigraphic images as a result of the favourable energy of its gamma radiation (140.5 keV)
openaire   +2 more sources

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